Is OCT angiography going to change our lives?

OCT jumped into our lives in 1991 when Huang and colleagues published about a “noninvasive cross-sectional imaging technology in biological systems.” Since then, major advancements have been made. Spectral-domain and swept-source OCT platforms brought faster scans and higher resolution. Also, OCT technology has been proposed in conjunction with adaptive optics, which may allow further resolution, up to a single photoreceptor cell. Polarized light combined with high-resolution OCT scanning may improve characterization of the retinal pigment epithelium. No doubt, therefore, that with the introduction of OCT, assessment of fundus structure has dramatically increased.Amelioration of knowledge on retinal function is also possible thanks to OCT. Functional ultrahigh-resolution OCT may allow the study of retinal response to light stimulation. Quantitative imaging of fundus blood flow and pulsatility of retinal and choroidal vasculature has been proposed with color Doppler OCT.

OCT angiography provides noninvasive close-up viewing of retinal vasculature

Over the past 20 years, OCT has developed rapidly as a noninvasive method of retinal imaging. OCT angiography, or OCTA, is the latest evolution of this technology, allowing extreme close-up imaging of the retinal vasculature for assessing retinal vascular diseases, and holds potential for guiding treatment decisions and monitoring patient responses to therapy.“The huge progress consists in having both functional and morphological assessment from a single dye-less examination. The rapid and noninvasive nature of the OCTA allows an easier follow-up of morphological and functional changes in prolonged, repetitive and even monthly evaluations.” Gabriel J. Coscas, MD, emeritus professor of ophthalmology at the University of Paris XII in Créteil, France, said.