ENV515 appears safe in removal of cataracts in glaucoma patients

LAS VEGAS — ENV515 travoprost XR intracameral implant appeared to be safe when used during cataract removal in patients with glaucoma, according to phase 2a clinical trial findings presented here. “All patients completed the study per protocol with no early discontinuations,” Tom R. Walters, MD, said at the American Academy of Ophthalmology annual meeting. “One hundred percent of implants were safely removed and aqueous humor was sampled for drug level analysis.”

Study of SPK-RPE65 gene therapy shows gains in visual acuity

LAS VEGAS — SPK-RPE65 treatment may result in rapid postoperative recovery of visual acuity for RPE65-mediated inherited retinal dystrophies, according to a presentation here. Albert M. Maguire, MD, discussed the phase 3 study’s primary and secondary endpoints, and presented additional results for the gene therapy at the American Academy of Ophthalmology annual meeting.