Clinical trials accumulate data for novel anti-VEGF

CHICAGO — A new anti-VEGF indicated for use in wet age-related macular degeneration achieved clinically meaningful and durable vision improvement in several studies with reduced dosing, according to a speaker here.Conbercept, a fusion protein produced in a manner similar to Elyea (aflibercept, Regeneron) is approved for use in China, and discussions are underway to bring this drug to the U.S. and other countries, Peter K. Kaiser, MD, told colleagues at the Retina Subspecialty Day preceding the American Academy of Ophthalmology meeting.

DALK improves vision in eyes with <i>Acanthamoeba</i> keratitis scarring

CHICAGO – Deep anterior lamellar keratoplasty showed promise in restoring vision in eyes with significant corneal scarring from Acanthamoeba keratitis, a speaker said here.DALK should be considered early as a treatment option in cases with active, resistant infection that are unresponsive to medical treatment, Caterina Sarnicola, MD, said at the American Academy of Ophthalmology meeting.

DMEK yields fast visual recovery for endothelial dysfunction

CHICAGO — Six-year midterm results showed Descemet’s membrane endothelial keratoplasty for the treatment of endothelial dysfunction provides fast and potentially complete visual recovery, a speaker said here.“With our cohort, visual acuity improvements were quite impressive, and by 6 months, more than 95% of patients achieved 20/40 vision,” Fook Chang Lam, MBChB, MRCP, FRCOphth, said at the American Academy of Ophthalmology meeting.

ACA has moderate effect on ophthalmology

CHICAGO — The Affordable Care Act has had a modest impact on ophthalmology so far, but a few unknown factors remain, an expert said at the American Academy of Ophthalmology meeting here.“As for ophthalmology, the impact to date has certainly been less than imagined and less than feared. There are, however, great risks in the future based on the growth of health exchange products,” Michael X. Repka, MD, AAO medical director for governmental affairs, said in a symposium.