Eyegate receives patent approvals for delivery system, pharmaceutical formulation

The U.S. Patent and Trademark Office issued a Notice of Allowance for a patent application related to Eyegate Pharmaceuticals’ Eyegate II Delivery System with pre-filled drug applicator, the company announced in a press release.The patent is for a delivery device containing a hydrogel applicator used to transport therapeutic substance across and/or through the eye, the release said.

Eleven Biotherapeutics completes patient enrollment for phase 3 study of isunakinra

Eleven Biotherapeutics has completed patient enrollment for the pivotal phase 3 study of isunakinra in patients with allergic conjunctivitis, the company announced in a press release. Isunakinra (EBI-005) is a topical interleukin-1 receptor blocker under study for use in moderate to severe allergic conjunctivitis. A total of 258 patients were randomized 1:1 to receive treatment with isunakinra or vehicle control in the multicenter, double-masked study. Safety and efficacy will be evaluated for up to 4½ weeks.

Make the Diagnosis: Ocular Oddity

(MedPage Today) — Case Findings: A 45-year-old male presents with blurred vision in the left eye. He has no prior history of eye disease. The results of a fundoscopy showed lines of crystalline deposits following the path of the retinal arterioles.