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NICE, France — Segmentation errors on spectral-domain OCT imaging might be correlated with microstructure abnormalities in the retinas of patients with a history of ROP and ROP treatment, further explaining why these patients develop poor vision despite a normal fundus appearance. In previous OCT studies, Wei-Chi Wu, MD, PhD, had already demonstrated that the eyes of prematurely born children have a steeper corneal curvature, a shallow anterior chamber and a thicker lens. They also have a less prominent foveal depression resulting from incomplete fovealization and a thinner choroid that brings less oxygen and fewer nutrients to the retina.

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