After decades of research, Kamra inlay offers cornea-based treatment for presbyopia

We now have our first FDA-approved intracorneal inlay for the surgical treatment of presbyopia, the AcuFocus Kamra inlay. I have been involved with research in the field of intracorneal lenses for the treatment of refractive errors for more than 30 years, and the journey to approval of the Kamra inlay is an enlightening example of the trials and tribulations of the innovation cycle.My first introduction to intracorneal lenses for the treatment of refractive error was at Southend-on-Sea in England in the clinic of Mr. Peter Choyce. Choyce was implanting polysulfone inlays into the cornea for the treatment of high myopia, and I saw many patients with up to –15 D of myopia have quite excellent outcomes. Further investigation also revealed many failures, with vascularization of the cornea, corneal melts and extrusion. In reviewing the literature, I learned that Jose Barraquer, MD, himself had investigated synthetic corneal inlays for the treatment of aphakia, and many other researchers, including John Henderson, MD, the former chairman at Mayo Clinic, also made similar attempts with different materials.

LUMINOUS interim analysis shows high intercountry variability of baseline characteristics

NICE, France — The second interim analysis at 3 years of the LUMINOUS study showed high diversity of baseline characteristics across distinct geographies in terms of patient age, interval from diagnosis to treatment, and prevalence of pigment epithelium detachment and polypoidal choroidal vasculopathy. “The LUMINOUS study has now reached the target enrollment of 30,000 patients. The purpose of this analysis was to describe the baseline characteristics of 17,546 patients with neovascular AMD across multiple countries recruited prior to March 2014,” Paul Mitchell, MD, said at the Euretina meeting.

Euretina Lecture focuses on cystoid maculopathies and role of OCT

NICE, France — The Euretina Lecture this year focused on cystoid maculopathies and the revolution that OCT has brought into the understanding of cystoid macular changes.The history of cystoid macular edema is closely linked to blood-retinal barrier (BRB) studies and the advent of fluorescein angiography at the end of the 1960s, Alain Gaudric, MD, emeritus professor in the Department of Ophthalmology at the Lariboisière Hospital, University of Paris 7, said.