Purpose: To describe the anatomic and functional outcomes in a cohort of subjects undergoing vitrectomy for retinal detachment (RD) resulting from myopic macular hole (MH) and to analyze the prognostic and surgical factors predicting retinal reattachment and MH closure.Design: Retrospective case series.Participants: All patients who underwent vitrectomy for RD resulting from myopic MH between 2000 and 2009 at our center.Methods: Case records were reviewed at 6 months after surgery. Retinal reattachment and complete anatomic success, defined as retinal reattachment with MH closure, were assessed. Multivariate logistic regression models, including age, gender, duration of symptoms, spherical equivalent refraction (SE), internal limiting (Read more...)
Choroidal Melanocytosis Evaluation with Enhanced Depth Imaging Optical Coherence Tomography – Corrected Proof
Objective: To assess eyes with unilateral choroidal melanocytosis using enhanced depth imaging (EDI) optical coherence tomography (OCT).Design: Retrospective, observational case series.Participants: Fifteen patients with unilateral choroidal melanocyto…
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Rituximab offered little therapeutic benefit in Graves’ ophthalmopathy
SAN JUAN, Puerto Rico — In a randomized, double blind, placebo-controlled trial, rituximab did not effect significant clinical improvement in Graves’ ophthalmopathy and had a 50% success/failure rate in patients with the disease.“In patients with active, moderate-to-severe, progressive Graves’ ophthalmopathy, for approximately 1 year duration, rituximab does not offer a therapeutic benefit,” Marius N. Stan, MD, of the Mayo Clinic in Rochester, Minn., said. “The other side is 50% of patients improved in both groups.”
Chloral Hydrate Safely Sedates Children for Eye Exams
Chloral hydrate (CH) may be a good alternative to general anesthesia in children who can’t cooperate with detailed eye exams, according to a new study. Reuters Health Information
The Effect of Socioeconomic Deprivation on Corneal Graft Survival in the United Kingdom – Corrected Proof
Objective: To investigate the effect of socioeconomic deprivation on cornea graft survival in the United Kingdom.Design: Retrospective cohort study.Participants: All the recipients (n = 13 644) undergoing their first penetrating keratoplasty (PK) re…
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Blood or urine test pinpoints genetic mutations linked to retinitis pigmentosa
A blood or urine sample may be analyzed to identify genetic mutations associated with retinitis pigmentosa.Retinitis pigmentosa patients were found to have mutations in the dehydrodolichol diphosphate synthase (DHDDS) gene, a key enzyme in the production of dolichols, a type of lipid in cells of the body, according to a news release from Bascom Palmer Eye Institute.“The biomarkers we discovered are a functional readout of dolichol metabolism. We can now assess whether dolichol biosynthesis is impaired by a simple biochemical test of a blood or urine sample,” Byron L. Lam, (Read more...)