GALILEO results show visual acuity gains diminished with less frequent monitoring

SEATTLE — Visual improvements gained during the fixed dosing period of intravitreal aflibercept injection in the GALILEO trial were not sustained once an as-needed dosing regimen was implemented with reduced monitoring frequency, according to 18-month results presented here.“These results indicate a potential added benefit with earlier treatment,” Yuichiro Ogura, MD, PhD, said at the Association for Research in Vision and Ophthalmology meeting.

Phaco-trab, phaco-AIT yield similar outcomes up to 2 years

SEATTLE — Up to 2 years, patient outcomes were comparable after phacoemulsification trabeculectomy, or phaco-trab, or after phacoemulsification ab interno trabeculectomy, or phaco-AIT, according to a speaker here. After 2 years, however, phaco-trab success was greater. “We hypothesized that there would be a greater effect or success rate with the phaco-trab but enhanced safety with phaco-AIT,” Douglas J. Rhee, MD, said at the Association for Research in Vision and Ophthalmology meeting.

Punctum plugs deliver sustained fluoroquinolone after cataract surgery

SEATTLE — Moxifloxacin-loaded punctum plugs delivered and maintained moxifloxacin levels in the tear fluid above the minimum inhibitory concentration for common susceptible pathogens for 7 days after cataract surgery, according to a poster here.“Consistent and therapeutic dosing from the punctum plug may be advantageous over patient-administered topical drops to avoid relapse, reduce contagion and cure the disease,” Michael Bassett and colleagues said in a poster presented at the Association for Research in Vision and Ophthalmology meeting.

Microperimetry, OCT used together to correlate retinal structure and function

SEATTLE — A weak relationship correlating local retinal sensitivity with local retinal thickness was found using a combination optical coherence tomography and microperimetry instrument, according to a poster here.“For treatment to be approved, there needs to be a functional benefit,” SriniVas R. Sadda, MD, told Ocular Surgery News at the Association for Research in Vision and Ophthalmology meeting, adding that the study was an effort to build on correlations between structure and function.