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The Molecular Basis Of Touch Sensation

2012/02/22

By Medical News Today

A gene known to control lens development in mice and humans is also crucial for the development of neurons responsible for mechanosensory function, as neurobiologists of the Max Delbruck Center for Molecular Medicine (MDC) Berlin-Buch have now discovered. They found that in mice in which they had removed the c-Maf gene in the nerve cells, touch sensation is impaired...

AMD Update 17: Dame Judi Dench Has Macular Degeneration

2012/02/22

Over the weekend, several articles appeared in the British press and also here in the States, about Dame Judi Dench announcing that she has macular degeneration – dry in one eye and wet in the other – and that she was going blind, although she was receiving treatment for the wet AMD in the hopes of preserving some of her sight in that eye.

I considered writing about this, but couldn’t find the right words – then I read what my friend Steve Rose of the Foundation Fighting Blindness had written on his blog, Eye on the Cure – and (Read more...)

Keeping Up With the Progress of Progressive Lenses

2012/02/21

Zeiss-Individual

Progressive lenses made their commercial debut in the middle of the last century. Also known as progressive addition lenses (PAL), the lenses enable eyeglass wearers to transition from distance to near vision without the image jumping when the eyes shift from one distance zone to another. They also have a cosmetic benefit: there is no line as there (Read more...)

Braille-Like Texting App Eliminates Need To Look At Mobile Screen

2012/02/21

By Medical News Today

Imagine if smartphone and tablet users could text a note under the table during a meeting without anyone being the wiser. Mobile gadget users might also be enabled to text while walking, watching TV or socializing without taking their eyes off what they're doing...

Stem Cells in Ophthalmology Update 17: Recent ACT Updates

2012/02/21

While I was out of the country on vacation, Advanced Cell Technology issued four news releases about their ongoing human embryonic stem cell trials. Here is a compilation of what transpired during my absence.

Jan. 25, 2012 -- ACT Announces that Additional Patient with Stargardt's Disease Has Undergone Embryonic Stem Cell Transplantation at UCLA's Jules Stein Eye Institute

Advanced Cell Technology announced the dosing of an additional patient in its Phase 1/2 trial for Stargardt's macular dystrophy using retinal pigment epithelial (RPE) cells derived from human embryonic stem cells (hESCs). The patient was treated on Tuesday (Jan. 24) by Steven (Read more...)

New Easy-to-Use Device Enhances Ocular Drug Delivery

2012/02/20

A device that employs an electric field enhances the delivery of dexamethasone to the anterior chamber of the eye.
Medscape Medical News

Video Games Improve Eyesight

2012/02/20

By Medical News Today

How we perceive the world tells us a lot about how the brain processes sensory information. At the meeting of the American Association for the Advancement of Science (AAAS) in Vancouver, McMaster University psychologist Daphne Maurer reported on how vision develops in individuals born with cataracts in both eyes...

Dame Judi Dench Determined To Beat Macular Degeneration

2012/02/18

By Medical News Today

Actor of film and stage, Dame Judi Dench, now filming her seventh James Bond film, Skyfall, where she plays 007's MI5 boss M, has given a moving interview where she talks about her determination to beat macular degeneration, an eye condition that is the leading cause of blindness in the western world. The interview, with UK's Daily Mirror, was published on Saturday...

Current Resources: The Use of Stem Cells and Gene Therapy in Ophthalmology

2012/02/18

As many of you are aware, over the past couple of years, I’ve been tracking and reporting on the companies and institutions involved in research and clinical trials using both stem cells and gene therapy in ophthalmology. With the help of several industry sources, I have been able to put together the most comprehensive and up-to-date list of who is involved and what they are doing.

Because I have been updating this information almost on a daily basis, I’ve decided to no longer post the information on this Journal (Irv Arons’ Journal), as it is practically out-of-date almost (Read more...)

Mobius selects The Apothecary Shops as distribution partner for Mitosol Kit for Ophthalmic Use

2012/02/18

By The Medical News

Apothecary Shop Wholesale, Inc., an affiliate of The Apothecary Shops Specialty Pharmacies, has received exclusive distribution rights from Mobius Therapeutics, LLC for its new drug Mitosol (mitomycin for solution) 0.2 mg/vial Kit for Ophthalmic Use.

UH’s Eye Institute receives $5M Elisabeth Severance Prentiss Foundation gift

2012/02/18

By The Medical News

The Elisabeth Severance Prentiss Foundation again has demonstrated its commitment to University Hospitals (UH) with a $5 million gift for the Eye Institute. The gift will honor the late Benjamin L. Millikin, MD, husband of Julia Severance and the grandfather of Prentiss Foundation trustee Elisabeth Alexander.

World Ophthalmology Congress (WOC) 2012

2012/02/17

Read clinically focused news coverage of key developments from the meeting.
Medscape Ophthalmology

Ranibizumab Outcomes at 2 Years: Are They Holding Up?

2012/02/17

The 2-year follow-up results are in for intravitreal ranibizumab in the treatment of diabetic macular edema.
Medscape Ophthalmology

NHS Choices assessment of press reports that sight problems predicted to rise in UK

2012/02/16

By NeLM - Ophthalmology

Source: NHS Choices
Area: News
NHS Choices has conducted an assessment of press reports, including one in the Daily Express that "the UK could face a 'bindness epidemic' caused by progressive eye conditions that is being grossly underestimated by the NHS." The story is based on a study that estimates the number of people affected by advanced age-related macular degeneration (AMD), the most common cause of age-related sight loss in the developed world. AMD is thought to affect half of the 370,000 people registered as blind or partially sighted in the UK. The study estimates that the current UK prevalence of late stage AMD is actually 2.4% of the adult population (513,000 cases) and that this figure is set to rise by one-third over the next decade, totalling nearly 700,000 cases by 2020. The study, funded by the Macular Diseases Society, was carried out by researchers from the University of London and the findings were published in the British Journal of Opthalmology. The assessment notes ...

Ranibizumab for diabetic macular oedema: results from 2 RCTs (RISE and RIDE)

2012/02/16

By NeLM - Ophthalmology

Source: Ophthalmology
Area: News
The efficacy and safety of intravitreal ranibizumab in diabetic macular oedema (DMO) has been evaluated in two parallel, methodologically identical, phase III, studies (RISE and RIDE). The studies involved adults with vision loss from DMO (best-corrected visual acuity [BCVA], 20/40 to 20/320 Snellen equivalent) and central subfield thickness ? 275 microm on time-domain optical coherence tomography (OCT). They were randomised to receive monthly intravitreal ranibizumab (0.5 or 0.3 mg) or sham injections. Macular laser was available per-protocol-specified criteria. The main outcome measure was the proportion of patients gaining ?15 letters in BCVA from baseline at 24 months. The following findings were reported: . In RISE, 377 patients were randomised (127 to sham, 125 to 0.3 mg, 125 to 0.5 mg). At 24 months, 18.1% of sham patients gained ? 15 letters vs. 44.8% of 0.3mg (adjusted difference vs. sham 24.3%; p<0.0001); and 39.2% of 0.5mg ...

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