Month: April 2013

Prismatic correction can result in positive motor outcomes in esotropic children

Prismatic correction led to successful motor outcomes while maintaining or improving stereo acuity in children with consecutive esotropia and prior unilateral recession and resection surgery, according to a study.The retrospective cohort study analyzed 105 patients with esodeviation of 5 ∆D or greater at 4 weeks after undergoing unilateral recession and resection surgery by the same surgeon. All patients were fitted with prism glasses with a minimum postoperative follow-up of 2 years. Average patient age was 4.7 years.

Characterization of a Clinician–Scientist Cohort in Ophthalmology: A Demographic Analysis of K Grant Awardees in Ophthalmology – Corrected Proof

Objective: To analyze ophthalmologists who are National Institutes of Health (NIH) K grant awardees to characterize clinician–scientists in ophthalmology.Design: Cohort study.Participants: Ophthalmologists who have received a K award from 1996 through 2010.Methods: K08 and K23 grant awardees were identified through the NIH Research Portfolio Online Reporter database. Information including gender, institution, educational degrees, and success in obtaining an R01 grant was analyzed.Main Outcome Measures: Receipt of an R01 grant.Results: One hundred five ophthalmologists were identified who received K08 or K23 grants from the National Eye Institute from 1996 through 2010. Overall, 75% of these were male, although 43% of K awardees (Read more...)

Wide-Field Fundus Autofluorescence Imaging of Retinitis Pigmentosa – Corrected Proof

Purpose: To evaluate the clinical usefulness of wide-field fundus autofluorescence (FAF) imaging in patients with retinitis pigmentosa (RP).Design: Cross-sectional case series.Participants: Seventy-five eyes of 75 patients with RP.Methods: We examined the eyes of the RP patients using the Optos 200Tx imaging system (Optos PLC, Dunfermline, United Kingdom) and identified abnormal FAF patterns such as ring hyperautofluorescence and patchy hypoautofluorescent areas. Patients with hyperautofluorescent rings or foveal hyperautofluorescence were compared with those without such findings. We determined the percentage area occupied by the FAF abnormalities within a defined region of the eye and examined the relationship between the percentage area of (Read more...)

Cataract Extraction Outcomes and the Prevalence of Zonular Insufficiency in Retinitis Pigmentosa – Corrected Proof

Purpose: To examine surgical outcomes in patients with retinitis pigmentosa (RP) undergoing phacoemulsification cataract extraction.Design: Retrospective observational case series.Patients And Methods: In this single-institution study of consecutive RP patients who underwent phacoemulsification cataract extraction and intraocular lens implantation by a single surgeon between 2002 and 2012, preoperative, intraoperative, and postoperative records were analyzed with attention to best-corrected visual acuity (BCVA), lens and zonular status, capsular tension ring use, incidence of posterior capsular opacification and neodymium-doped yttrium-aluminum-garnet (YAG) laser capsulotomy, and surgical complications.Results: Eighty eyes of 47 RP patients (21 male) underwent cataract surgery during the study period at an average (Read more...)

The Value of Combining Autofluorescence and Optical Coherence Tomography in Predicting the Visual Prognosis of Sealed Macular Holes – Corrected Proof

Purpose: To investigate the autofluorescence patterns of sealed macular holes and determine the correlations of the postoperative changes in spectral-domain optical coherence tomography and fundus autofluorescence (FAF) with the best-corrected visual acuity (BCVA) of patients with sealed idiopathic macular holes.Design: Retrospective consecutive observational case series.Methods: Seventy-seven eyes from 75 consecutive patients who had undergone successful vitrectomies for idiopathic macular holes by a single surgeon with postoperative follow-ups for over 1 year were included. FAF imaging studies were performed 1 month and 6 months post surgery, and optical coherence tomography (OCT) was performed at regular intervals after surgery. The main outcome measures were (Read more...)

Ocular Biometric Parameters Associated With Intraocular Pressure Reduction After Cataract Surgery in Normal Eyes – Corrected Proof

Purpose: To evaluate the ocular biometric parameters associated with intraocular pressure (IOP) reduction after phacoemulsification.Design: Prospective, observational case series.Methods: The study included 999 patients who had undergone uncomplicated phacoemulsification. IOP and ocular biometric parameters were checked preoperatively and 3 months postoperatively using anterior segment optical coherence tomography, optical biometry, and ultrasonic biomicroscopy. The relationship between IOP change and the parameters, including preoperative IOP, anterior chamber depth, axial length, angle opening distance at 500 μm, anterior chamber area, corneal thickness, lens thickness, and iris thickness at 750 μm, was evaluated.Results: The mean patient age was 67.1 ± 4.3 years. The average change in IOP (Read more...)

Comparisons of Outcomes With Different Intervals Between Adjunctive Ranibizumab and Photodynamic Therapy for Polypoidal Choroidal Vasculopathy – Corrected Proof

Purpose: To determine the optimal time for administration of intravitreal ranibizumab injections before photodynamic therapy (PDT) as combined therapy to treat polypoidal choroidal vasculopathy (PCV).Design: Retrospective, comparative, interventional case series.Methods: The study included 99 eyes (98 patients) with treatment-naïve subfoveal PCV treated with an intravitreal ranibizumab injection followed by PDT. The combination therapy included 1 ranibizumab injection administered 7 days before PDT (7-day group) or 2 days before PDT (2-day group). All eyes were followed for over 12 months.Results: Intravitreal ranibizumab was administered 7 days before PDT in 59 eyes and 2 days before PDT in 40 eyes. In the 7-day group, the best-corrected visual (Read more...)