Reticular Pseudodrusen

In 1990, our group first described reticular pseudodrusen as a peculiar yellowish pattern in the macula of age-related macular degeneration (AMD) patients, whose visibility was enhanced using blue light. More recently, using spectral-domain optical coherence tomography (SD-OCT), Zweifel et al demonstrated that discrete collections of hyperreflective material located not under (as typical of drusen in AMD), but above the retinal pigment epithelium (RPE), were associated with reticular pseudodrusen. Interestingly, the analysis of integrated imaging allowed our group to show that the peculiar yellowish pattern was responsible for reticular hyperreflectivity on (Read more...)

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