Immunogammopathies and Acquired Vitelliform Detachments: A Report of Four Cases – Accepted Manuscript

Abstract: Purpose: To describe the nature and evolution of acquired macular detachments in patients with immunogammopathies and to propose a mechanism for their development.Design: Retrospective observational case series.Methods: Three patients with multiple myeloma and one with light chain deposition disease were diagnosed with vitelliform macular detachments based on clinical exam, fundus autofluorescence, fluorescein angiography, and optical coherence tomography. These patients were followed over time and their clinical exams and imaging studies were compared and contrasted.Results: Three patients (5 eyes) with multiple myeloma and 1 patient (2 eyes) with light chain deposition disease presented with acquired macular yellowish subretinal deposits on (Read more...)

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