SAN FRANCISCO β Severe obstructive sleep apnea may be associated with more severe diabetic macular edema, leading to refractory DME, according to a speaker here.
βIn a JAMA study in 2017, [the authors found] when hypoxia occurs, it will directly increase the secretion of VEGF from retinal pigment epithelial cells. Based on this, we suspected there might be some relation between [obstructive sleep apnea] and DME,β Jui-Fan Chiang, MD, said at the American Academy of Ophthalmology annual meeting.
A retrospective study of patients at Chang Gung Memorial Hospital in Taiwan
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