Phentolamine mesylate ophthalmic solution may have utility in presbyopia

Phentolamine mesylate ophthalmic solution improved distance corrected near visual acuity and reduced pupil diameter in patients with glaucoma and presbyopia, according to a study.
“Presbyopia has a significantly negative impact on quality of life. ... Currently, there are no pharmacological therapies approved for presbyopia, but there is some evidence that decreasing pupil diameter, optimally to a size of 1.6 mm to 2 mm to create a ‘pinhole’ effect, can improve visual acuity by increasing the depth of focus via pseudoaccommodation,” Jay S. Pepose, MD, PhD, and

Full Story →