Abstract: Purpose: To report the outcomes of current vitreoretinal surgical management of proliferative sickle retinopathy and to compare current methods to previous studies.Design: A retrospective, interventional case series.Methods: Fifteen eyes of 1…
Author: Am J Ophthalmol
Clinical Utilization of Anti-VEGF Agents and Disease Monitoring in Neovascular Age-Related Macular Degeneration – Accepted Manuscript
Abstract: Purpose: To examine bevacizumab and ranibizumab utilization and disease monitoring patterns in patients with neovascular age-related macular degeneration (neovascular AMD) in clinical practice.Design: Retrospective medical claims analysis.Met…
Clinical Characteristics of Reticular Pseudodrusen in Korean Patients
We read the article entitled “Clinical Characteristics of Reticular Pseudodrusen in Korean Patients,” by Lee and associates. In their article, the authors present the clinical characteristics of reticular pseudodrusen in Korean patients.
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Intravitreal Bevacizumab for Symptomatic Retinal Arterial Macroaneurysm
I offer the following observations regarding the recent study by Cho and associates. Intravitreal bevacizumab for exudative complications of retinal artery macroaneurysm was first reported in 2009. Since then, there have been several reports indicating…
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We appreciate Dr Kishore’s interest in our recently published manuscript. He questioned the use of bevacizumab (1.25 mg/0.05 mL; Avastin; Genentech Inc, San Francisco, California, USA) for the treatment of subfoveal hemorrhage secondary to retinal arte…
Cataract Surgery in Glaucoma Patients: How Much Benefit?
In this issue of the Journal, Drs. Slabaugh, Bojikian, Moore, and Chen report the effects of phacoemulsification cataract surgery on intraocular pressure in their patients with medically-controlled open-angle glaucoma. Ophthalmologists are keenly inter…
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We appreciate the interest and comments on our article. The spectral-domain optical coherence tomography (SD OCT) scan image from a 64-year-old woman in Figure 2 might be similar to adult-onset vitelliform dystrophy. However, the final diagnosis was m…
Reporting Visual Acuities
The AJO encourages authors to report the visual acuity in the manuscript using the same nomenclature that was used in gathering the data provided they were recorded in one of the methods listed here. This table of equivalent visual acuities is provided…
The Investment in Cataract Surgery Yields Healthy Rewards
Unoperated cataract remains the most common cause of blindness worldwide, even though the disorder can be effectively and inexpensively treated with a standard surgical procedure. Visual impairment attributable to unoperated cataract has been reported …
Effect of nepafenac eye drops on intraocular pressure – a randomized prospective study – Accepted Manuscript
Abstract: Purpose: To report the effect of nepafenac (0.1%) eye drops on intraocular pressure in eyes with cataract.Design: Prospective, randomized clinical trial.Methods: Three hundred and twenty-seven patients with bilateral cataracts in an institutional setting were included. All patients had a baseline intraocular pressure (IOP) ≤21 mmHg without a history of intraocular surgery in past 3 months. One eye of each individual was randomized to the treatment group with the other eye acting as a control. Nepafenac (0.1%) eye drops were instilled 3 times a day in the eye that received treatment. Intraocular pressure (IOP) with Goldmann applanation tonometer (GAT) was (Read more...)
Ocular phenotype analysis of a family with biallelic mutations in the BEST1 gene – Accepted Manuscript
Abstract: Purpose: To investigate the genetic cause and perform a comprehensive clinical analysis of a Danish family with autosomal recessive bestrophinopathy. To investigate whether Bestrophin may be expressed in normal human retina.Design: Retrospect…
Distinct microRNA-155 expression in the vitreous of patients with primary vitreoretinal lymphoma and uveitis – Accepted Manuscript
Abstract: Purpose: To use micro- ribonucleic acid (microRNA) profiles in the vitreous for differential diagnosis of primary vitreoretinal lymphoma and uveitis. Design: A prospective cross-sectional study designMethods: This prospective cross-section st…
Relationship between Preferred Sleeping Position and Asymmetric Visual-field Loss in Open-angle Glaucoma Patients – Accepted Manuscript
Abstract: Purpose: To investigate the relationship between preferred sleeping position and asymmetric visual-field (VF) loss in open-angle glaucoma (OAG) patients.Design: Retrospective, cross-sectional study.Methods: Six hundred and ninety-two (692) pa…
Comparison of Hoffer Q and Haigis Formulae for Intraocular Lens Power Calculation according to the Anterior Chamber Depth in Short Eyes – Accepted Manuscript
Abstract: Purpose: To compare the accuracy of the Hoffer Q and Haigis formulae according to the anterior chamber depth (ACD) in cases of short axial length (AL).Design: Retrospective cross-sectional studyMethods: A total of 75 eyes from 75 patients with an AL of less than 22.0 mm implanted with an Acrysof IQ intraocular lens (IOL) were enrolled. The median absolute errors (MedAEs) predicted by the Hoffer Q and Haigis formulae were compared. The correlations between ACD and the predicted refractive error calculated using the two formulae were analyzed.Results: There were no significant differences in the MedAEs predicted by the Hoffer Q (Read more...)
Effect of scan quality on diagnostic accuracy of spectral domain optical coherence tomography in glaucoma – Accepted Manuscript
Abstract: Purpose: To evaluate the effect of scan quality on the diagnostic accuracies of optic nerve head (ONH), retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) parameters of spectral domain optical coherence tomography (SD-OCT) in glaucoma.Design: Cross-sectional study.Methods: 252 eyes of 183 control subjects (mean MD: -1.84 dB) and 207 eyes of 159 glaucoma patients (mean MD: -7.31 dB) underwent ONH, RNFL and GCC scanning with SD-OCT. Scan quality of SD-OCT images was based on signal strength index (SSI) values. Influence of SSI on diagnostic accuracy of SD-OCT was evaluated by receiver operating characteristic (ROC) regression.Results: Diagnostic accuracies (Read more...)
Choroidal neovascularization associated with focal choroidal excavation – Accepted Manuscript
Abstract: Purpose: To describe the clinical and imaging characteristics of choroidal neovascularization (CNV) accompanied by focal choroidal excavation.Design: Retrospective, interventional case series.Methods: The medical records of 16 patients (16 ey…
Intraoperative Anterior Segment Optical Coherence Tomography: A Novel Assessment Tool during Deep Anterior Lamellar Keratoplasty – Corrected Proof
Purpose: To describe the use of high-resolution anterior segment optical coherence tomography (AS-OCT) during deep anterior lamellar keratoplasty (DALK).Design: Prospective case series.Methods: At the Singapore National Eye Centre we performed sequenti…
Vitreoretinal Complications and Vitreoretinal Surgery in Osteo-Odonto-Keratoprosthesis Surgery – Corrected Proof
Purpose: To describe the indications for and approaches to vitreoretinal surgery in patients with osteo-odonto-keratoprosthesis (OOKP).Design: Retrospective case series.Methods: This was a retrospective review of all patients who had undergone OOKP sur…
Conjunctival Flora Antibiotic Resistance Patterns After Serial Intravitreal Injections Without Postinjection Topical Antibiotics – Corrected Proof
Purpose: To report conjunctival bacterial flora antibiotic resistance patterns after serial intravitreal injections performed using a povidone-iodine preparation without the use of preinjection or postinjection topical antibiotics.Design: Prospective, …