Aerpio Pharmaceuticals has completed a reverse merger transaction with Aerpio Therapeutics Inc. and Aerpio Acquisition Corp. that resulted in Aerpio Pharmaceuticals continuing the historical business of Aerpio Therapeutics, according to a company press…
Author: Healio ophthalmology
PUBLICATION EXCLUSIVE: Improving efficiency in the operating room
New ophthalmology residents sometimes mistakenly think that performing a surgery quickly is the key to doing more cases in a day. On the contrary, rushing a surgical procedure can result in a higher complication rate and less desirable outcomes, which …
ACP, AAFP express concerns about Trump’s ‘skinny’ budget proposal
The ACP and the American Academy of Family Physicians recently released statements about President Donald J. Trump Administration’s Fiscal Year 2018 budget outline, voicing deep concerns about its proposed reductions to medical and health services research, primary care training programs and many other essential health care programs and research, as well as its implications for patients’ health, safety and access to care. “The United States has long been recognized as a world leader in medical research and education,” Nitin S. Damle, MD, MS, MACP, president of ACP, said in a (Read more...)
Spark Therapeutics reports $123.7 million net loss in 2016
Spark Therapeutics reported a net loss of $123.7 million, or $4.29 per share, in 2016 compared with a net loss of $47.8 million, or $2.10 per share, in 2015, according to a company press release.Revenue in 2016 was $20.2 million, all from an agreement …
Study highlights potential of alternative anti-inflammatory agent
A single postoperative injection of XG-102 was non-inferior to dexamethasone eye drops in the management of surgery-induced ocular inflammation in a phase 2 randomized, controlled trial. The study, which was carried out at six sites in France, randomized 145 eyes of 145 patients undergoing anterior or posterior segment surgery into three groups, receiving XG-102 (brimapitide, Xigen) 90 µg, XG-102 900 µg or dexamethasone eye drops administered four times a day for 21 days. XG-102 was administered by subconjunctival injection at the end of surgery.
AMA, ACS, AHA, ADA to Congress: Slow down, reconsider AHCA
At a recent National Press Club event, the AMA, American Cancer Society Cancer Action Network, American Diabetes Association and American Heart Association expressed concerns regarding President Donald J. Trump’s proposed health care law, the American Health Care Act. The groups emphasized the negative impact the act will have on millions of Americans, particularly those with chronic health conditions, including cancer, diabetes, heart disease and stroke.Earlier this week, the Congressional Budget Office (CBO) released a report that projected the American Health Care Act (AHCA) will cause millions of Americans to lose (Read more...)
AMA approves extensions for three Category III CPT codes for MIGS devices
The AMA has granted a 5-year extension to three Category III CPT codes that describe insertion of aqueous drainage devices into the anterior chamber of the eye using microinvasive glaucoma surgery, according to a Glaukos press release.The extension, good through Dec. 31, 2023, includes 0191T, which describes the insertion of an initial anterior segment aqueous drainage device into the trabecular meshwork, such as Glaukos’ iStent; 0253T, which describes insertion of an anterior segment aqueous drainage device into the suprachoroidal space, such as the iStent Supra; and 0376T, which is an (Read more...)
Serious health threats possible with underregulated commercial stem cell clinics
Stem cells hold potential benefits for the treatment of age-related macular degeneration, but commercial stem cell clinics that skirt under FDA regulations and oversights can pose serious health threats to patients, according to an editorial in the New…
Frequent anti-VEGF injections may be associated with increased risk of glaucoma surgery
A large pharmacoepidemiologic study carried out in British Columbia found that seven or more intravitreal injections of bevacizumab are associated with an increased risk of glaucoma surgery.Using population-based Ministry of Health-supported databases,…
EyeGate reports $13.3 million net loss in 2016
EyeGate Pharmaceuticals reported a $13.3 million net loss in 2016 compared with an $8.4 million net loss in 2015, according to a company press release.Research and development costs were $8.4 million compared with $2.7 million in 2015, an increase attr…
Allergan, Editas Medicine enter research and development agreement
Allergan and Editas Medicine have entered into a strategic research and development alliance, according to a joint press release from the companies.The agreement will give Allergan exclusive access and the option to license up to five of Editas’ genome-editing ocular programs, including Leber congenital amaurosis (LCA10).
Woman presents with cloudy declining vision and flashes
A 56-year-old Caucasian woman presented with painless, slowly decreasing “murky” vision in the left eye over a period of 3 weeks, along with flashes. Her ocular history was positive for hemorrhagic posterior vitreous detachment after blunt trauma with a basketball to the same eye 4 months earlier. On that exam, she was also noted to have “fullness of the optic nerve, venous beading and inferior drusen OS.” Despite the physician’s recommendation to return after 4 to 6 weeks, the patient was lost to follow-up until new visual symptoms started. She (Read more...)
Youths with diabetes at higher risk for retinopathy
Youths with type 1 or type 2 diabetes are at a higher risk of being diagnosed with diabetic retinopathy later in life and should undergo early ophthalmic examinations.These at-risk youths are at a higher risk to be diagnosed with diabetic retinopathy (…
Shire reports quick uptick in Xiidra prescriptions
At the end of 2016, about 1,000 physicians each week were joining the ranks of those newly prescribing Xiidra for dry eye disease, according to the head of the company that launched the medication last year.Flemming Ornskov, MD, CEO of Shire, spoke of …
Which DRCR.net protocol has had the biggest impact on your practice?
PointIf I had to pick only one study that has had the biggest impact on my current practice among the many important multicenter randomized clinical trials carried out by DRCR.net, it would be Protocol I. At the time of study, anti-VEGF agents were bei…
Worse visual outcomes correspond to higher rate of refractive growth in aphakic children
A higher rate of refractive growth is associated with worse visual outcomes in eyes left aphakic after infant cataract surgery, according to a study.That association did not occur in eyes that had received IOLs after the surgery.
Dry eye disease in the surgical patient
“If you diagnose dry eye before you operate, it is your patient’s problem. If you diagnose it postoperatively, it is your problem.”–Eric Donnenfeld
NICUs slow to embrace telemedicine for ROP screening
Many neonatal intensive care units have difficulty enlisting ophthalmologists to screen for retinopathy of prematurity, but most are not yet convinced telemedicine can help fill the void, according to a study.Even so, the authors of the survey on trend…
ASCRS Research Council aims to mirror success of DRCR.net
The Diabetic Retinopathy Clinical Research Network is a collaboration among the National Eye Institute, the National Institute of Diabetes and Digestive and Kidney Diseases, industry and more than 400 committed retina specialists at 120 practices. The …
Ophthalmology-based treatments may have effect on seasonal affective disorder
Welcome to another edition of CEDARS/ASPENS Debates. CEDARS/ASPENS is a joint society of cornea, cataract and refractive surgery specialists, here to discuss some of the latest hot topics in ophthalmology.As we endure the cold winter months with short …