Abstract: Purpose: To compare refractive state changes in eyes implanted with toric intraocular lenses (IOLs) versus non-toric IOLs, after cataract extraction.Design: Retrospective, comparative.Methods: In a single-institution, 121 eyes underwent phacoemulsification and implantation with either non-toric IOLs (AcrySof® IQ SN60WF) or toric IOLs (AcrySof® Toric IOL). The spherical value, cylindrical value, spherical equivalent (SE) of refractive error, and visual acuity were measured preoperatively and 1, 3, and 6 months after surgery. Main outcome measures were the pattern of changes of spherical, cylindrical, and SE values based on postoperative time, between different IOL types.Results: The groups included patients who underwent surgery with (Read more...)
Clinic-Based Glaucoma Care in the Era of Surgical Subspecialization – Accepted Manuscript
Abstract: Purpose: To evaluate the impact of surgeon practice profile on clinic-based glaucoma care.Design: Population-based study of glaucoma care patterns in Ontario, Canada from 2000 to 2010.Methods: Using comprehensive physician services data from the Ontario Health Insurance Plan database, ophthalmologists were divided into five surgical practice subgroups. The role of each subgroup in the provision of glaucoma care was evaluated. Consultations and office visits were used to assess non-surgical care, while laser trabeculoplasty procedures were used to assess clinic-based procedural care.Results: Between 2000 and 2010, the population rate of glaucoma consultations and follow up visits provided by ophthalmologists who do (Read more...)
DNA Mismatch Repair Defects and Microsatellite Instability Status in Periocular Sebaceous Carcinoma – Accepted Manuscript
Abstract: Purpose: To characterize mismatch repair protein expression and the role of DNA repair abnormalities in sebaceous carcinomas of the ocular adnexa.Design: This was a retrospective, case series studyMethods: We reviewed ten cases of sporadic se…
Corneal cross-linking: Intrastromal riboflavin concentration in iontophoresis-assisted imbibition versus traditional and transepithelial techniques – Accepted Manuscript
Abstract: Purpose: The present study aimed at determining differences in riboflavin concentration in the anterior, intermediate and posterior stroma after three corneal cross-linking imbibition techniques (standard Epi-off, Epi-on and Iontophoresis-assisted administration) of 0.1% riboflavin.Design: Experimental laboratory investigation of human cadaver corneas not suitable for transplantation.Methods: 10 corneas underwent imbibition with Epi-on (n=3), Epi-off (n=3), iontophoresis (n=3) and saline exposure (control; n=1). Femtosecond laser was used to produce three 8mm discs of the superficial (0-150μm), intermediate (150-300μm) and deep stroma (>300μm). Riboflavin concentration was measured with High-Performance Liquid Chromatography. The main outcome measure was riboflavin concentration at the three evaluated depths.Results: (Read more...)
Immunogammopathies and Acquired Vitelliform Detachments: A Report of Four Cases – Accepted Manuscript
Abstract: Purpose: To describe the nature and evolution of acquired macular detachments in patients with immunogammopathies and to propose a mechanism for their development.Design: Retrospective observational case series.Methods: Three patients with mu…
Characteristics of rhegmatogenous retinal detachment after refractive surgery: Comparison with myopic eyes with retinal detachment – Accepted Manuscript
Abstract: Purpose: To evaluate the characteristics of rhegmatogenous retinal detachment (RD) in patients with previous laser in-situ keratomileusis (LASIK) and compared them to RD in patients with previous laser assisted sub-epithelial keratomileusis (…