Purpose: To compare the clinical outcomes of two treatment approaches for bilateral nasolacrimal duct obstruction (NLDO) in infancy.Design: Multicenter, randomized clinical trial.Methods: We studied 57 infants between the ages of 6 and <10 months who had bilateral NLDO. Participants were randomized to receive either (1) immediate office-based probing within two weeks (n = 31) or (2) 6 months of observation and nonsurgical management followed by surgical facility-based probing for unresolved cases (n = 26). Treatment success was defined as the absence of clinical signs of NLDO (epiphora, increased tear lake, mucous discharge) in both eyes on masked examination at 18 months of age.Results: In the (Read more...)
Cerepress Elucidates Intracranial Pressure from a Quirky Scan of Eye
Critically elevated intracranial pressure (ICP) represents the important cause of morbidity and mortality in patients with intracranial pathology, but measuring it has long been a problem because doing it effectively has required invasive methods that are not exactly practical on the sidelines of a football field or by a bedside.
Third Eye Diagnost (Read more...)
Pink Eye Tied to Poor Infection Control in Clinics (CME/CE)
(MedPage Today) — Six unrelated outbreaks of epidemic keratoconjunctivitis linked to human adenovirus underscore the importance of infection control measures in ophthalmology, according to the CDC.
Role of Corneal Collagen Cross-Linking in Pseudophakic Bullous Keratopathy: A Clinicopathological Study – Corrected Proof
Objective: To evaluate the clinical and histopathologic changes induced by collagen cross-linking (CXL) in pseudophakic bullous keratopathy (PBK).Design: Randomized, prospective, interventional study.Participants: Twenty-four patients with PBK were included in the study.Methods: Twenty-four patients with PBK underwent CXL followed by keratoplasty at 1 or 3 months. Twelve patients underwent penetrating keratoplasty 1 month after CXL (group A) and the remaining 12 patients underwent penetrating keratoplasty 3 months after CXL (group B). The main outcome measures were assessed at 1 week and 1 month for all patients and at 3 months for 12 patients only. The corneal buttons underwent histopathologic and immunofluorescence (Read more...)
Working-Age Cataract Patients: Visual Results, Reading Performance, and Quality of Life with Three Diffractive Multifocal Intraocular Lenses – Corrected Proof
Purpose: To compare the visual outcomes, reading performance, and quality of life (QoL) of working-age cataractous patients bilaterally implanted with 3 different diffractive multifocal intraocular lenses (MIOLs).Design: Two-center, randomized, prospective, double-masked study.Participants: Sixty-three consecutive patients (126 eyes) seen at Ophthalmology Section, Palermo and Florence University, Italy, randomized to receive the ReSTOR SN6AD3 (Alcon Laboratories, Inc, Irvine, CA) (20 patients, group A), ReSTOR SN6AD1 (Alcon Laboratories, Inc) (21 patients, group B), or TECNIS ZMA00 (Abbott Medical Optics, Santa Ana, CA) (22 patients, group C) MIOL.Intervention: Phacoemulsification.Main Outcome Measures: One-year follow-up differences among the 3 MIOL groups in visual acuity, reading performance by (Read more...)
Vascular Endothelial Growth Factor Gene and the Response to Anti-Vascular Endothelial Growth Factor Treatment for Choroidal Neovascularization in High Myopia – Corrected Proof
Purpose: To investigate the association between the vascular endothelial growth factor (VEGF) gene polymorphism and the response to anti-VEGF treatment for choroidal neovascularization (CNV) in highly myopic eyes.Design: Retrospective cohort study.Part…