Purpose: To estimate retinal ganglion cell (RGC) losses associated with visible glaucomatous localized retinal nerve fiber layer (RNFL) defects.Design: Observational cross-sectional study.Methods: A multicenter study of 198 normal eyes (138 subjects) and 66 glaucomatous eyes (55 subjects) recruited from the Diagnostic Innovations in Glaucoma Study and the African Descent and Glaucoma Evaluation Study. All eyes underwent standard automated perimetry (SAP), spectral-domain optical coherence tomography, and fundus stereophotography within 6 months. Glaucomatous eyes were included if localized RNFL defects were detected by masked grading of stereophotographs. The number of RGCs in each sector of a structure-function map was estimated using a previously (Read more...)
Analysis of Tear Cytokines and Clinical Correlations in Sjögren Syndrome Dry Eye Patients and Non–Sjögren Syndrome Dry Eye Patients – Corrected Proof
Purpose: To compare concentrations of tear cytokines in 3 groups composed of Sjögren syndrome (SS) dry eye, non–Sjögren syndrome (non-SS) dry eye, and normal subjects. Correlations between ocular surface parameters and tear cytokines were also investigated.Design: Prospective cross-sectional study.Methods: SS dry eye patients (n = 24; 40 eyes) were diagnosed with primary SS according to the criteria set by the American-European Consensus Group. Non-SS dry eye patients (n = 25; 40 eyes) and normal subjects (n = 21; 35 eyes) were also enrolled. Tear concentrations of interleukin (IL)-17, IL-6, IL-10, IL-4, IL-2, interferon γ (IFN-γ), and tumor necrosis factor α (TNF-α) were measured (Read more...)
The Impact on Vision of Aspheric to Spherical Monofocal Intraocular Lenses in Cataract Surgery: A Systematic Review with Meta-analysis – Corrected Proof
Purpose: To provide a summary of the impact on vision of an aspheric intraocular lens (IOL) compared with a spherical IOL in cataract surgery.Design: Systematic review with meta-analysis.Participants: Patients from published randomized controlled trial…
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Novel technique allows atraumatic removal of resistant cortical vitreous adhesions
COPENHAGEN, Denmark — A novel technique allows removal of strongly attached cortical vitreous in a minimal amount of time with no trauma, according to one surgeon.”Thorough removal of the cortical vitreous is essential in several surgical situations, such as [diabetic macular edema], macular hole and macular pucker,” Athanasios Nikolakopoulos, MD, said at the meeting of the European Society of Ophthalmology.
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2013 SOE congress opens in Copenhagen
COPENHAGEN, Denmark — Enlivened by the music of Verdi, Puccini, Lehar and Gershwin, the European Society of Ophthalmology congress was opened June 8 by SOE President Stefan Seregard, MD, PhD. In his speech, Seregard reminded the audience that the reason to gather at such a comprehensive and extensive congress is “to teach and learn for the benefit of the patients.”
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Keynote lecture focuses on heavy impact of late diagnosis of glaucoma
COPENHAGEN, Denmark — Late diagnosis of glaucoma is a widespread issue, leading to poorer prognosis, lower quality of life and higher expenses, according to the keynote lecturer here. “When diagnosed, the majority are still unaware of their condition. Undiagnosed patients were 90% in the Indian Aravind Eye Study, 60% in the Blue Mountains Eye Study and 55% in the Rotterdam Eye Study,” Roger Hitchings, MD, said at the meeting of the European Society of Ophthalmology.