Ranibizumab treatment was discontinued in 21% of neovascular age-related macular degeneration patients because of complete inactivation of choroidal neovascularization, a long-term study found.Fifteen percent of patients failed to respond to treatment,…
Month: January 2013
Alcon launches once-daily NSAID for pain, inflammation after cataract surgery
Alcon has launched Ilevro suspension, a topical NSAID that treats pain and inflammation related to cataract surgery.Ilevro (nepafenac ophthalmic suspension 0.3%) is indicated for once-daily dosing, according to an Alcon news release.
Bausch + Lomb begins phase 3 studies of glaucoma drug candidate
Bausch + Lomb has begun a pair of phase 3 clinical studies on latanoprostene bunod to reduce IOP in patients with glaucoma or ocular hypertension, according to a company news release.The drug candidate, licensed from Nicox and previously known as BOL-3…
Sutureless intrascleral IOL implantation an option for post-traumatic aphakia
Sutureless intrascleral IOL implantation improved vision in patients with post-traumatic aphakia, according to a study.The interventional case series included 26 eyes of 23 patients with acute traumatic cataract who were divided into two groups. The fi…
Reprogramming eye cells that enable night vision may one day treat retinitis pigmentosa
Doctors may one day treat some forms of blindness by altering the genetic program of the light-sensing cells of the eye, according to scientists at Washington University School of Medicine in St. Louis.
Fuchs’ Endothelial Corneal Dystrophy: Subjective Grading versus Objective Grading Based on the Central-to-Peripheral Thickness Ratio
Purpose:
To assess interobserver agreement between 2 corneal specialists grading Fuchs’ dystrophy clinically and to determine if the corneal central-to-peripheral thickness ratio (CPTR) may be an alternative and objective metric of disease severity.
Design:
Cross-sectional study.
Participants:
Forty-five eyes (26 subjects) with mild and moderate Fuchs’ dystrophy, 73 eyes (60 subjects) with advanced Fuchs’ dystrophy, and 267 eyes (142 subjects) with normal corneas.
Methods:
Corneas with Fuchs’ dystrophy were graded by 2 corneal specialists based on the confluence and area of guttae and the presence or absence of edema. Central (Read more...)
Functional Improvement after One- and Two-Eye Cataract Surgery in the Salisbury Eye Evaluation
Purpose:
To determine the impact that cataract and cataract surgery have on clinical measurements of vision, reading speed, objective mobility performance, and subjective visual functioning.
Design:
Prospective, population-based study.
Participants:
A total of 1739 Salisbury Eye Evaluation (SEE) participants without previous cataract surgery with bilateral baseline best-corrected visual acuity (BCVA) of logarithm of the minimum angle of resolution (logMAR) ≤0.3 (≥20/40) or cataract surgery between rounds 1 and 2.
Methods:
Participants were categorized on the basis of cataract surgery by round 2 into no surgery, unilateral surgery, or bilateral surgery. (Read more...)
Hydrus Microstent: A Promising New Approach
An ex vivo examination seeks to determine whether outflow facility can be increased with a microstent. Medscape Ophthalmology
Bausch + Lomb finalizes acquisition of Technolas Perfect Vision
With Bausch + Lomb’s completion of its acquisition of Technolas Perfect Vision, the new entity will be known as Bausch + Lomb Technolas, according to a company news release.“The Technolas Perfect Vision team, led by CEO Dr. Kristian Hohla, has built a ‘best in class’ femtosecond laser platform and other exciting ophthalmic products that round out Bausch + Lomb’s surgical product portfolio and position us to become a ‘one-stop shop’ for ophthalmic surgeons,” Brent Saunders, president and CEO of Bausch + Lomb, said in the release.
Plaque radiotherapy effective in managing iris melanoma
Plaque radiotherapy proved effective in managing patients with iris melanoma with a low risk for metastasis, according to a study.The retrospective case series included 144 patients with iris melanoma; 58 patients had secondary glaucoma at baseline exa…
BLOG: Sarcoidosis diagnosis and treatment
I have always been interested in sarcoidosis in the way it presents and its diagnostic dilemma, so I would like to pose three test questions and follow up with a discussion to build upon the questions.
Speaker: Corneal inlays moving closer to approval in US
WAIKOLOA, Hawaii — Two intracorneal inlays for the treatment of presbyopia may be nearing approval in the U.S., according to a speaker here.The ReVision Optics Raindrop inlay, composed of a disc of hydrogel that is implanted under a LASIK flap, is now completing its phase 3 U.S. Food and Drug Administration trial, OSN Cataract Surgery Section Editor John A. Hovanesian, MD, FACS, said at Hawaiian Eye 2013.
Study explores regular aspirin use and potential risks for macular degeneration
This week, a study published in the journal JAMA Internal Medicine, explored the connection between regular aspirin use and the potential risks for developing the blinding eye disease, macular degeneration. As a result, there is increased confusion and…
Histologic Basis of Variations in Retinal Pigment Epithelium Autofluorescence in Eyes with Geographic Atrophy
Purpose:
Lipofuscin contained in the retinal pigment epithelium (RPE) is the main source of fundus autofluorescence (FAF), the target of an imaging method useful for estimating the progression of geographic atrophy (GA) in clinical trials. To establi…
Seasonal Changes in Visual Field Sensitivity and Intraocular Pressure in the Ocular Hypertension Treatment Study
Purpose:
Longitudinal testing plays a key role in glaucoma management. Variability between visits hampers the ability to monitor progression. It has previously been shown that average intraocular pressure (IOP) exhibits seasonal fluctuations. This study examines whether visual field sensitivity also exhibits seasonal fluctuations and seeks to determine whether such fluctuations are correlated to seasonal IOP effects.
Design:
Comparative case series.
Participants:
A total of 33 873 visits by 1636 participants enrolled in the Ocular Hypertension Treatment Study. Participants were split into 6 geographic zones according to the prevailing climate in (Read more...)
FDA Clears iPhone App for Retinal Images
(MedPage Today) — An iPhone adapter with a companion app designed to make it easy to share high resolution images of the retinal nerve and fundus has received 510(k) clearance from the Federal Drug Administration.
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Extramacular scanning shows promise in uveitic disorders
New optical coherence tomography scanning protocols offer enhanced characterization of patients with birdshot chorioretinopathy, UK researchers report.
Lab Notes: New Target for Sepsis Lung Injury
(MedPage Today) — A newly recognized step in development of sepsis-induced lung injury looks like a promising therapeutic target, researchers suggested. Also this week: the need for light in utero.
High dietary intake of saturated fat associated with reduced semen quality among 701 young Danish men from the general population
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