Source: Cochrane
Area: Evidence > Drug Specific Reviews
Background
Atopic keratoconjunctivitis (AKC) is a chronic ocular surface non-infectious inflammatory condition that atopic dermatitis patients may suffer at any time point in the cours…
Author: NeLM - Ophthalmology
US FDA approves aflibercept injection (Eylea) for macular oedema following central retinal vein occlusion (CRVO)
Source: Reuters Health News
Area: News
According to a report by Reuters Health News, the US Food and Drug Administration (FDA) has approved aflibercept injection (Eylea) for macular oedema following central retinal vein occlusion (CRVO). The recommend…
CHMP adopts positive opinion for aflibercept (Eylea) solution for injection for the treatment of wet age-related macular degeneration
Source: EMA
Area: News
The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion, recommending the granting of a marketing authorisation for the medicinal product aflibercept (Eylea…
New online decision aids launched
Source: E-Health Insider
Area: News
The national Shared Decision Making Programme has launched five online patient decision aids, which have been designed and developed by Totally Health. The aids aim to help people think about healthcare decisions us…
Half-fluence photodynamic therapy (PDT) with verteporfin for chronic central serous retinopathy
Source: London and South East Regional Medicines Information Service
Area: Evidence > Reviews for Individual Funding Requests (IFRs)
Review completed for IFR panel September 2012 on Half-fluence photodynamic therapy (PDT) with verteporfin for chro…
Verteporfin photodynamic therapy for exudative (wet) age-related macular degeneration
Source: London and South East Regional Medicines Information Service
Area: Evidence > Reviews for Individual Funding Requests (IFRs)
Review completed for IFR panel August 2012 on Verteporfin photodynamic therapy for exudative (wet) age-related mac…
Intravitreal ranibizumab for macular oedema secondary to central retinal vein occlusion (CRVO) and glaucoma
Source: London and South East Regional Medicines Information Service
Area: Evidence > Reviews for Individual Funding Requests (IFRs)
Review completed for IFR panel September 2012 on Intravitreal ranibizumab for macular oedema secondary to central …
Horizon scanning: Novartis to seek EU approval of ranibizumab for myopic CNV
Source: PharmaTimes
Area: News
According to PharmaTimes, Novartis has announced that it will file for EU approval of ranibizumab for myopic choroidal neovascularisation (CNV) by the end of 2012, based on positive results from the REPAIR study. This on…
Prospective study of intraocular bevacizumab for macular oedema in central retinal vein occlusion
Source: Ophthalmology
Area: News
A small 12 month prospective study has found that intraocular injections of bevacizumab (AvastinT) are helpful in treating macular oedema (MO) secondary to central retinal vein occlusion (CRVO), as long as they’re giv…
National Eye Health Week launches free toolkit for supporters
Source: National Eye Health Week
Area: News
The third National Eye Health Week will take place on 17 – 23 September 2012. Eye care charities, organisations and health professionals from across the UK are joining together to promote the importance of e…
Risk of cataracts with ivacaftor (Kalydeco) reported in animal studies
Source: Reuters Health News
Area: News
The FDA has highlighted on its website the findings from a study in juvenile rats of the risk of developing cataracts with cystic fibrosis drug ivacaftor (Kalydeco). This information has been added to the label f…
Horizon Scanning: Orphan drug status granted for gevokizumab for the treatment of uveitis in the United States
Source: BioSpace
Area: News
BioSpace reports that the United States Food and Drug Administration (FDA) has granted Orphan Drug Designation to gevokizumab, an interleukin-1 beta modulating antibody, for the treatment of non-infectious intermediate, po…
Study suggests age-related cataract is associated with type 2 diabetes and statin use
Source: Optometry and Vision Science
Area: News
According to the results of a study published in the journal ‘Optometry and Vision Science’ that used data from a large optometric clinic population, statin use was substantially higher in patients with …
Help needed in medication self-management for people with visual impairment: case-control study
Source: British Journal of General Practice
Area: Evidence > Medicines Management > References
Background: Visual impairment (VI) is rising in prevalence and contributing to increasing morbidity, particularly among older people. Understa…
A safety review and meta-analyses of bevacizumab and ranibizumab in age related macular degeneration: Off-label versus gold standard
Source: PLoS One
Area: News
The authors of this paper carried out a systematic review based on randomised controlled clinical trials (RCTs) to assess whether unlicensed therapy with bevacizumab is as safe as licensed therapy with ranibizumab for the t…
Horizon scanning: Two phase 3 trials investigate enzymatic vitreolysis with ocriplasmin for vitreomacular traction and macular holes
Source: NEJM
Area: News
The results of two phase 3 trials investigating the use of intravitreal ocriplasmin in vitreomacular adhesion have been published in the New England Journal of Medicine (NEJM). In vitreomacular adhesion, the vitreous gel adhere…
Systematic review and indirect comparison of ranibizumab and bevacizumab in diabetic macular oedema
Source: BMJ
Area: News
There are no published trials directly comparing ranibizumab and bevacizumab for the treatment of diabetic macular oedema. To address this gap in knowledge, this systematic review indirectly compared the effectiveness of ranibiz…
UK Vision Strategy publishes joint strategic needs assessment for eye health needs of local populations
Source: UK Vision Strategy
Area: News
The UK Vision Strategy has published a joint strategic needs assessment (JSNA) template for health and wellbeing boards. The template will help boards to understand the eye health needs of their local populations …
Draft guidance from NICE does not support use of fluocinolone acetonide intravitreal implant for diabetic macular oedema
Source: NICE
Area: News
The National Institute for Health and Clinical Excellence (NICE) has issued draft recommendations for consultation, for the use of fluocinolone acetonide intravitreal implant for the treatment of diabetic macular oedema. The Ap…
Does the dose of intravenous fluorescein sodium need to be adjusted in renal impairment or renal replacement therapy?
Source: South West Medicines Information and Training
Area: Evidence > Medicines Q & A
Whilst limited data are available, it does not appear that dose adjustments are required in patients with renal impairment undergoing retinal angiography with u…