We were interested to see the cover photo on the August 2012 edition of Ophthalmology showing a fluorescein angiogram with findings attributed to macular telangiectasia type 1 (Coats’ disease). The wide field fluorescein angiogram very nicely demonstra…
Category: Peer-reviewed
Prevention of Neovascular Glaucoma
Neovascular glaucoma (NVG) is defined by the occurrence of neovascularization (NV) of the iris and/or anterior chamber angle associated with increased intraocular pressure (IOP). Optic disc changes are not specific and cupping of the optic nerve head i…
期刊一览
Richoz 等人 (p. 1354) 的一项长期随访研究发现角膜胶原交联术 (CXL) 可以有效阻止 LASIK 或准分子激光角膜切削术 (PRK) 术后角膜扩张的进展. 这一方法改善了患者最佳矫正远视力 (CDVA) 及最大K值 (Km…
Molecular Analysis of Uveal Melanoma
Onken et al report a prospective evaluation of a gene expression profiling (GEP)-based assay, designed around 15 genes, that assigns uveal melanoma (UM) to 2 prognostic subgroups: Classes 1 and 2, which respectively are associated with low and high ris…
Adaptive Optics Imaging of Idiopathic Epiretinal Membranes
Idiopathic epiretinal membrane (ERM) is the most common vitreomacular interface pathology in adult population. Prevalence of idiopathic ERM has been estimated to be >10% among those >70 years; its development is usually preceded by posterior vitreous detachment. It is composed of nonvascularized tissue growth along the retinal inner limiting membrane, and many different cellular (hyalocytes, glial cells, fibroblasts) and extracellular components (collagen, fibronectin, neurites) have been identified in immunocytochemical studies.
This Issue At A Glance
Long-term results from a study by Richoz et al (p. 1354) show that corneal collagen cross-linking (CXL) effectively halts the progression of ectasia that has occurred after LASIK or photorefractive keratectomy (PRK). The procedure improves the correcte…
Author reply
We appreciate the opportunity to respond to the letter by Coupland and Damato regarding our 2012 article. Contrary to their claim, the gene expression profile (GEP) prognostic test for uveal melanoma has undergone much greater validation than any other…
Adenoid Cystic Carcinoma of the Lacrimal Gland: Rare … Lethal … Cured?
There are few more difficult conversations in ophthalmology than that between a surgeon and a patient with newly diagnosed adenoid cystic carcinoma of the lacrimal gland. The results of conventional treatment, most commonly orbital exenteration followe…
Author reply
In response to the letter by Chen et al, we disagree with many of their assumptions and statements. We respond point-by-point to their concerns. In our published study, endophthalmitis was defined by the presence of positive intraocular cultures in a…
A Simple Vista en Este Número
Los resultados a largo plazo de un estudio realizado por Richoz y otros (p. 1354) muestran que el enlace cruzado de colágeno corneal (CXL) detiene efectivamente la progresión de la ectasia producida después de LASIK o de queratectomía fotorrefracti…
Author reply
We appreciate the interest shown by Carifi et al regarding our article. The volume of intracameral phenylephrine (IPH) injected (0.6 ml), means we can be sure that enough amount of drug is administered, because part of the drug will be released through…
Contents
Ciliary Body Lymphangiogenesis
With interest we read the recent article by Khan et al investigating the ciliary body for the presence of peritumoral lymphatic vessels in uveal melanoma with and without extraocular extension. This study confirms previous findings by Birke et al on th…
Author reply
We appreciate the comments of Cereda et al regarding our article, “Highly reflective foveal region in optical coherence tomography in eyes with vitreomacular traction or epiretinal membrane.”
Phacoemulsification versus Trabeculectomy in Medically Uncontrolled Chronic Angle-Closure Glaucoma without Cataract
We read with interest the article by Tham et al on phacoemulsification versus trabeculectomy in medically uncontrolled chronic angle-closure glaucoma without cataract. We appreciate their discussion on the specific benefits and drawbacks of both phacoe…
Author reply
I thank Dr Wilkinson for his interest in my article. He questioned whether the location of retinal breaks developing with posterior vitreous detachment (PVD) after phacoemulsification in eyes with lattice degeneration were associated with the lattice d…
Vitreous Detachments after Phacoemulsification Surgery
I enjoyed reading the informative paper by Hikichi and have a single simple question regarding this important information. The data: Retinal tears occurred in 6.4% of eyes after development of a posterior vitreous detachment. These tears were signifi…
Gene Expression Profiling versus TNM Classification
We appreciate the opportunity to respond to the letter from Kivelä and Kujala regarding our recent article that prospectively evaluated a gene expression profile (GEP) prognostic test for uveal melanoma. One of us (J.W.H.) was a primary member of the …
Author reply
We thank Dr Kawada for his insightful comments. It is not uncommon to find differences in the association between risk factors and (1) prevalent disease and (2) incident disease. These associations need to be interpreted differently. Risk factor associ…
Keratitis-Induced Endophthalmitis
We read with great interest the article by Henry et al, which describes infectious keratitis progressing to endophthalmitis. This report provided us with valuable information on endophthalmitis contiguously spreading from keratitis. The study was simpl…