Intravitreal Bevacizumab at 4-Month Intervals for Prevention of Macular Edema after Plaque Radiotherapy of Uveal Melanoma – Corrected Proof

Purpose: To evaluate the efficacy of intravitreal bevacizumab for prevention of macular edema after plaque radiotherapy of uveal melanoma.Design: Retrospective, single-center, nonrandomized, interventional comparative study.Participants: Patients with uveal melanoma treated with plaque radiotherapy were divided into 2 groups: a bevacizumab group and a control group.Intervention: The bevacizumab group received intravitreal bevacizumab injection at the time of plaque removal and every 4 months thereafter for 2 years (total, 7 injections). The control group had no intravitreal bevacizumab injection. Both groups had periodic follow-up with ophthalmoscopy and optical coherence tomography (OCT).Main Outcome Measures: Development of OCT-evident macular edema.Results: There were 292 patients (Read more...)

Femtosecond cataract surgery not more cost-effective than conventional phaco

Femtosecond laser-assisted cataract surgery was not more cost-effective than conventional phacoemulsification, according to an Australian study.Investigators conducted a retrospective cost-effectiveness analysis of femtosecond laser-assisted cataract surgery and phacoemulsification cataract surgery in a hypothetical cohort of patients. They converted visual acuity outcomes to utility values based on quality-adjusted life-years (QALYs).