TORONTO — Safety profiles of intravitreal ranibizumab injections were shown to be consistent with the established systemic safety profile of ranibizumab, according to a presenter here. “Intravitreally, there are concerns about the possibility of systemic adverse events, but we haven’t really been able to calculate accurately because of sample size,” Baruch D. Kuppermann, MD, told colleagues at the American Society of Retina Specialists meeting here. To overcome that barrier, a pairwise comparison of 14 phase 2/3 randomized clinical trials was undertaken, looking in particular for serious adverse events occurring after (Read more...)
Localized RNFL defects linked to retinal ganglion cell loss in glaucomatous eyes
Localized retinal nerve fiber layer defects were associated with high neuronal losses, according to a study.The study comprised patients who participated in the African Descent and Glaucoma Evaluation Study and the Diagnostic Innovations in Glaucoma St…
Near infrared, short wavelength autofluorescence predict retinal layer changes
Near infrared and short wavelength autoflourescence imaging can anticipate outer retinal layer alterations in OCT scans, a study found.The retrospective observational case study comprised 91 eyes of 86 patients with a history of resolved central serous…
BLOG: Extra caution needed in cataract surgery for retinitis pigmentosa cases
Patients with retinitis pigmentosa develop cataracts earlier in life and surgery for these patients presents some challenges. While these patients have relatively soft cataracts, primarily with posterior subcapsular changes, there are other aspects whi…
Impact of Age-related Change of Retinal Nerve Fiber Layer and Macular Thicknesses on Evaluation of Glaucoma Progression – Corrected Proof
Objective: To investigate the impact of age-related change of macular and circumpapillary retinal nerve fiber layer (RNFL) measurements on evaluation of glaucoma progression.Design: Prospective, longitudinal study.Participants: A total of 150 eyes of 9…
The Relationship between Better-Eye and Integrated Visual Field Mean Deviation and Visual Disability – Corrected Proof
Objective: To determine the extent of difference between better-eye visual field (VF) mean deviation (MD) and integrated VF (IVF) MD among Salisbury Eye Evaluation (SEE) subjects and a larger group of glaucoma clinic subjects and to assess how those me…