Peer-reviewed

Peripheral Lesions Identified by Mydriatic Ultrawide Field Imaging: Distribution and Potential Impact on Diabetic Retinopathy Severity – Corrected Proof

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Objective: To assess diabetic retinopathy (DR) as determined by lesions identified using mydriatic ultrawide field imaging (DiSLO200; Optos plc, Scotland, UK) compared with Early Treatment Diabetic Retinopathy Study (ETDRS) 7-standard field film photography.Design: Prospective comparative study of DiSLO200, ETDRS 7-standard field film photographs, and dilated fundus examination (DFE).Participants: A total of 206 eyes of 103 diabetic patients selected to represent all levels of DR.Methods: Subjects had DiSLO200, ETDRS 7-standard field film photographs, and DFE. Images were graded for severity and distribution of DR lesions. Discrepancies were adjudicated, and images were compared side by side.Main Outcome Measures: Distribution of hemorrhage and/or (Read more...)

Peer-reviewed

Macular Imaging in Highly Myopic Eyes With and Without Glaucoma – Corrected Proof

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Purpose: To determine how evaluations of macular structures on spectral-domain optical coherence tomography compare with those of the optic disc and circumpapillary retinal nerve fiber layer (RNFL) in discriminating between highly myopic eyes with and without glaucoma.Design: Retrospective, comparative study.Methods: The appearances of ganglion cell layer and RNFL on Spectralis macular scans (Heidelberg Engineering) and optic disc on photographs were evaluated by 2 observers. The receiver operating characteristic regression was conducted for macular ganglion cell complex and circumpapillary RNFL measurements on RTVue-100 (Optovue).Results: Ninety highly myopic eyes (−6.0 to −15.0 diopters; mean deviation [MD], −5.6 ± 5.1 dB) and 91 non–highly myopic (Read more...)