What are the most effective management strategies for perforating injuries of the globe? International Ophthalmology Clinics
Month: October 2013
Remote Screening for Vision Loss From Diabetes
Could the VA’s successful teleretinal imaging program improve diabetic eye care throughout the nation? Medscape Optometry
SD-OCT detects signs of silicone oil emulsification
Optical coherence tomography detected small hyper-reflective areas in eyes that underwent silicone oil tamponade for various indications, according to a study. The retrospective study included 11 eyes of 11 patients. Vitrectomy and silicone oil tampona…
DSEK may be option in children with congenital hereditary endothelial dystrophy
Descemet’s stripping endothelial keratoplasty can be an alternative to penetrating keratoplasty in children with congenital hereditary endothelial dystrophy, offering early visual stabilization and a low risk of complications.In the retrospective, comparative, interventional study, five patients had a mean age of 6.6 years and underwent PK in one eye and DSEK in the fellow eye.
Expedited FDA reviews examined in new study
Of the drugs approved by the FDA in 2008, those that received expedited reviews were approved more quickly, were studied in fewer patients and still have unanswered safety questions, according to new data published in JAMA Internal Medicine.“Under the Obama administration, the FDA may also change the testing requirements for many drugs prior to approval; the stated rationales are promoting innovation and reducing the time and cost of discovering new drugs,” researchers wrote. “To inform the debate about the appropriate standards for testing new drugs, we studied the development times, (Read more...)
Older open-angle glaucoma patients face increased risk of bilateral blindness
Older patients with a long-term diagnosis of open-angle glaucoma had an increased risk of bilateral blindness, according to a study. The retrospective chart review included 592 glaucoma patients in Sweden who died between January 2006 and June 2010. Pa…
Enzymatic vitreolysis could mark beginning of new era in treating vitreomacular interface diseases
Pharmacotherapy may set a new standard of care for symptomatic vitreomacular adhesion and vitreomacular traction-related macular hole, according to recent findings. Read more in the October issue of OSN Europe Edition. Get the whole story
NEI-funded study explores methods to improve diagnosis, treatment of common eye diseases
If you’ve ever been sleep-deprived, you’ve probably had a firsthand glimpse of the blood vessels in your eyes. But what you haven’t seen—and what many eye care professionals cannot see as well as they would like—are the vessels closest to the retina, the light-sensitive tissue at the back of the eye.
Vision problems in young children accurately identified by portable vision screening devices
Portable screening devices allow pediatricians to successfully screen children for vision problems, including amblyopia, according to an abstract presented at the American Academy of Pediatrics (AAP) National Conference and Exhibition in Orlando. Appro…
Choose Your Tests Wisely: Advice From the AAO
Medscape interviewed Dr. William Rich about participation in Choosing Wisely, a multisociety initiative to educate physicians and patients on recommendations for certain questionable practices. Medscape Ophthalmology
A Branch Retinal Vein Occlusion: aka BRVO
A branch retinal vein occlusion reduces vision by causing macular edema. Treating the macular edema may improve vision.
A 57-Year-Old Woman With Sjögren Syndrome
A 57-year-old woman With Sjögren syndrome, fibromyalgia, and rheumatoid arthritis presented with worsening vision. What should be done to improve her vision and eye comfort?
Medscape Optometry
Presbyopia Correction: LASIK vs Inlays
Which provides a better opportunity to surgically correct presbyopia: LASIK or corneal inlays? Dr. Roger Steinert explores both options in this discussion. Medscape Ophthalmology
Surgical Debulking for Idiopathic Dacryoadenitis: A Diagnosis and a Cure – Corrected Proof
Purpose: Idiopathic inflammatory tumor of the lacrimal gland, also called idiopathic dacryoadenitis, generally is treated with high-dose, long-term systemic corticosteroids, despite their limited success, high recurrence rate, and incidence of drug-ind…
Management and Outcome of Retinoblastoma with Vitreous Seeds – Corrected Proof
Purpose: To report the treatment response of retinoblastoma with vitreous seeds to high-dose chemotherapy coupled with periocular carboplatin.Design: Retrospective, interventional case series.Participants: Consecutive patients with retinoblastoma with …
Long-Term, Drug-Free Remission of Sympathetic Ophthalmia with High-Dose, Short-Term Chlorambucil Therapy – Corrected Proof
Objective: To evaluate the safety and effectiveness of short-term, high-dose chlorambucil therapy in achieving long-term, drug-free remission in the treatment of sympathetic ophthalmia (SO).Design: Retrospective case series.Participants: Sixteen patien…
Association of CAV1/CAV2 Genomic Variants with Primary Open-Angle Glaucoma Overall and by Gender and Pattern of Visual Field Loss – Corrected Proof
Purpose: The CAV1/CAV2 (caveolin 1 and caveolin 2) genomic region previously was associated with primary open-angle glaucoma (POAG), although replication among independent studies has been variable. The aim of this study was to assess the association b…
Long-Term Trends in Glaucoma-Related Blindness in Olmsted County, Minnesota – Corrected Proof
Objective: To determine the longitudinal trends in the probability of blindness due to open-angle glaucoma (OAG) in Olmsted County, Minnesota, from 1965 to 2009.Design: Retrospective, population-based cohort study.Participants: All residents of Olmsted County, Minnesota (aged ≥40 years) who were diagnosed with OAG between January 1, 1965, and December 31, 2000.Methods: All available medical records of every incident case of OAG were reviewed until December 31, 2009, to identify progression to blindness, defined as visual acuity ≤20/200 or visual field constriction to ≤20°. Kaplan–Meier analysis was used to estimate the cumulative probability of glaucoma-related blindness. Population incidence of blindness within 10 years of (Read more...)
The Future of Uveitis Treatment – Corrected Proof
Purpose: Uveitis is a heterogeneous collection of diseases with polygenic and environmental influences. This heterogeneity presents challenges in trial design and selection of end points. Despite the multitude of causes, therapeutics targeting common i…
Corneal Topographic and Tomographic Analysis of Fellow Eyes in Unilateral Keratoconus Patients Using Pentacam – Corrected Proof
Purpose: To evaluate topographic and tomographic changes in fellow eyes in unilateral keratoconus (KCN) patients by comparing them with normal eyes.Design: Retrospective comparative case series.Methods: Fourteen eyes of 14 patients with unilateral KCN and 34 eyes of 34 refractive surgery candidates were divided into 3 diagnostic groups using a Pentacam rotating Scheimpflug camera: advanced KCN eyes of unilateral KCN (KCN group, 14 eyes), normal fellow eyes of unilateral KCN (fellow eye group, 14 eyes), and refractive surgery candidates (normal group, 34 eyes). Topographic and tomographic parameters, which were obtained from Pentacam using sagittal curvature, elevation, and corneal thickness maps, were (Read more...)