Category: Peer-reviewed

Erratum

With apologies from the authors, in the publication entitled, “Clinical Applications of Cost Analysis of Diabetic Macular Edema Treatments” (Ophthalmology 2012;119:2558–62) had errors. Corrected (with corrected numbers in bold) is printed below.

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We thank Parekh and associates for their thoughtful comments and interesting description of a case of blood reflux during cataract surgery 2 years after previous Trabectome surgery. The authors raised several plausible mechanisms for intraoperative blo…

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We thank Firth and associates for their interest in our article. They suggest that the mechanism behind the change in accommodation during binocular viewing among the patients with intermittent exotropia is the result of convergence accommodation, rath…

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We thank Vazirani and associates for their interest in our series documenting persistent corneal edema after collagen cross-linking (CXL) for keratoconus. Gokhale was the first to report corneal edema after CXL for keratoconus. Bagga and associates rep…

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We greatly appreciated Dr Jonas’ interest in and comments on our recent study, and we thank him for sharing his experience in the treatment of complicated retinal arterial macroaneurysms with intravitreal bevacizumab. Dr Jonas raises an important point…

Reporting Visual Acuities

The AJO encourages authors to report the visual acuity in the manuscript using the same nomenclature that was used in gathering the data provided they were recorded in one of the methods listed here. This table of equivalent visual acuities is provided…

This Issue At A Glance

Campochiaro 等 (p. 795) 进行了一项研究, 视网膜中央静脉阻塞 (CRVO) 或视网膜分支静脉阻塞 (BRVO) 伴有黄斑水肿的患者, 其视网膜无灌注区 (RNP) 进展情况与阻断血管内皮生长因子 (VEGF) 之间的关系,

This Issue At A Glance

A study by Campochiaro et al (p. 795) assessing the relationship of blocking vascular endothelial growth factor (VEGF) on progression of retinal nonperfusion (RNP) in patients with macular edema due to central retinal vein occlusion (CRVO) or branch re…

Anatomic Features and Function of the Macula and Outcome of Surgical Tenotomy and Reattachment in Achiasma – Corrected Proof

Objective:
To examine the anatomic features and function of the macula in achiasma and to compare visual acuity, eye movements, foveation, and eye velocity before and after tenotomy and reattachment (T&R) surgery.

Design:
Case series.

Participants:
Two children with isolated achiasma.

Methods:
Ophthalmologic examinations, brain magnetic resonance imaging, full-field and multifocal electroretinography (ERG), visual evoked potentials (VEPs), spectral-domain optical coherence tomography (OCT), eye-movement recordings, and unilateral T&R in 1 patient.

Main Outcome Measures:
Visual acuity before and after surgery, macular anatomic features and function, and eye velocity before and after T&R surgery in 1 patient.

Results:
Magnetic resonance imaging and VEP confirmed absence of decussation of retinofugal fibers in both patients. Visual acuity was 20/100 and 20/200. The anatomic features and function of the fovea and macula were normal by OCT and multifocal ERG. After T&R, there was a marked reduction in horizontal eye velocity and monocular visual acuity improved to 20/80.

Conclusions:
The finding that the macula is normal in achiasma suggests that reduced acuity is the result of retinal image motion from nystagmus. Two-muscle T&R reduces horizontal retinal image motion and can improve visual acuity in achiasma or patients with infantile nystagmus.

Financial Disclosure(s):
The author(s) have no proprietary or commercial interest in any materials discussed in this article.

Ability of Cirrus High-Definition Spectral-Domain Optical Coherence Tomography Clock-Hour, Deviation, and Thickness Maps in Detecting Photographic Retinal Nerve Fiber Layer Abnormalities – Corrected Proof

Purpose:
To investigate the ability of clock-hour, deviation, and thickness maps of Cirrus high-definition spectral-domain optical coherence tomography (HD-OCT) in detecting retinal nerve fiber layer (RNFL) defects identified in red-free fundus photographs in eyes with early glaucoma (mean deviation >–6.0 dB).

Design:
Cross-sectional study.

Participants:
Two hundred ninety-five eyes with glaucomatous RNFL defects with clear margins observed in red-free fundus photographs and 200 age-, sex-, and refractive error–matched healthy eyes were enrolled.

Methods:
The width and location of RNFL defects were evaluated by using the red-free fundus photograph. When a RNFL defect detected by red-free fundus photograph did not present as (1) yellow/red codes in the clock-hour map, (2) yellow/red pixels in the deviation map, or (3) blue/black areas in the thickness map, the event was classified as a misidentification of a photographic RNFL defect by Cirrus HD-OCT. In healthy eyes, the presence of false-positive RNFL color codes of Cirrus HD-OCT maps was investigated.

Main Outcome Measures:
The prevalence of and factors associated with the (1) misidentification of photographic RNFL defects by Cirrus HD-OCT in eyes with glaucoma and (2) false-positive RNFL color codes of Cirrus HD-OCT maps in healthy eyes were assessed.

Results:
Among the 295 red-free fundus photographic RNFL defects from 295 eyes with glaucoma, 83 (28.1%), 27 (9.2%), and 0 (0%) defects were misidentified in the clock-hour, deviation, and thickness maps of Cirrus HD-OCT, respectively. Fifty-six defects (19.0%) were misidentified only in the clock-hour map and 27 (9.2%) in both the clock-hour and deviation maps. The misidentification of photographic RNFL defects by Cirrus HD-OCT was associated with a narrower width and a temporal location of RNFL defects (P<0.05). Among the 200 healthy eyes, 25 (12.5%), 30 (15.0%), and 12 (6.0%) eyes had false-positive RNFL color codes in clock-hour, deviation, and thickness maps of Cirrus HD-OCT, respectively.

Conclusions:
Among the clock-hour, deviation, and thickness maps obtained with Cirrus HD-OCT, the thickness map showed the best diagnostic ability in detecting photographic RNFL defects. The RNFL thickness map may be a useful tool for the detection of RNFL defects in eyes with early glaucoma.

Financial Disclosure(s):
The authors have no proprietary or commercial interest in any of the materials discussed in this article.