Chronic ocular hypertension may occur after repeated intravitreal anti-VEGF injections

PARIS — Repeated intravitreal anti-VEGF injections might cause chronic ocular hypertension in some patients, according to a study. “The exact mechanism is still unknown, but we may hypothesize a correlation with the repeated occurrence of transient acute IOP elevation that follows [intravitreal] injection. Alteration of the aqueous outflow may also be caused by the presence of silicone oil droplets or protein aggregates in the trabecular meshwork or by an autoimmune reaction leading to chronic trabeculitis,” Emilie Agard, MD, said at the meeting of the French Society of Ophthalmology.

Iontophoresis in transepithelial cross-linking undergoing clinical study in France

PARIS — Three of the French Centers of Reference for Keratoconus, namely Bordeaux, Brest and Toulouse, are currently engaged in the clinical application of iontophoresis in transepithelial collagen cross-linking. More centers are expected to join the project shortly. “Iontophoresis uses electrical current to enhance penetration of riboflavin into the cornea. Animal experiments have been carried out with encouraging results, and we are now ready to apply the technique in the human eye,” Myriam Cassagne, MD, said at the meeting of the French Society of Ophthalmology.

Minimally invasive sclerotomy procedure shows stable results in long term

PARIS — High-frequency deep sclerotomy is a safe, minimally invasive glaucoma procedure that effectively lowers IOP, according to one specialist.By decreasing the resistance of the trabecular meshwork, high-frequency deep sclerotomy allows aqueous outflow into Schlemm’s canal, Bojan Pajic, MD, explained at the meeting of the French Society of Ophthalmology. Using a diathermic probe (Abee Glaucoma Tip, Oertli Instruments) with an external diameter of 0.8 mm, bipolar radiofrequency energy is applied through the trabecular meshwork into Schlemm’s canal and then 1 mm into the sclera.

New multifocal IOL designs offer better solutions at all distances

PARIS — Compared with previous models, more recent multifocal implants have refined the refractive transition from the center to the periphery, providing satisfactory intermediate vision. “IOLs like the Oculentis Lentis Mplus, the Zeiss At Lisa trifocal and bifocal, and the PhysIOL FineVision belong to this new generation. They provide useful vision for the many people who work with computers nowadays,” Michael Assouline, MD, said at the meeting of the French Society of Ophthalmology.