We appreciate the interest of Shah and colleagues in our recent article. They have made some excellent suggestions regarding our study and its application in clinical practice. They point out, as we did in our original study, that contact ultrasonic me…
Author: Am J Ophthalmol
A 5-Year Audit of Cataract Surgery Outcomes After Posterior Capsule Rupture and Risk Factors Affecting Visual Acuity – Corrected Proof
Purpose: To describe the posterior capsule rupture rates and visual outcomes after phacoemulsification, analyze risk factors for poor vision, and compare results of faculty (F) and residents (R).Design: Retrospective audit study.Methods: Visual success of all capsule ruptures (2006-2010) was analyzed and compared to uneventful cases. Rupture rates of faculty and residents were compared (χ², P < .05). Success was defined as % best-corrected visual acuity (BCVA) ≥20/40 at 3 months (excluding poor-prognosis eyes) and studied in relation to age, sex, surgeon type, stage of surgery, vitreous loss, dropped nucleus, and other complications (eg, retinal detachment, corneal decompensation, dislocated intraocular lens [IOL]). (Read more...)
Risk Factors Associated With Night Vision Disturbances After Phakic Intraocular Lens Implantation – Corrected Proof
Purpose: To investigate the incidence and severity of night vision disturbances after implantable collamer lens surgery and to analyze the risk factors.Design: Retrospective, noncomparative study.Methods: Medical charts from 50 eyes of 25 patients who …
Indications and Outcomes of Intraocular Lens Exchange During a Recent 5-Year Period – Corrected Proof
Purpose: To analyze and classify the indications, clinical presentations, and surgical outcomes of intraocular lens (IOL) exchange performed in a recent 5-year period.Design: Retrospective, interventional case series.Methods: setting: Private clinical practice. study population: Chart records of 57 eyes of 53 consecutive patients who had undergone IOL exchange between May 2007 and December 2011 were reviewed. observation procedures and main outcome measures: The preoperative clinical characteristics, treatment parameters, intraoperative and postoperative complications, and pre- and postoperative logarithm of the minimal angle of resolution (logMAR) best-corrected visual acuity (BCVA) were recorded and analyzed.Results: IOL dislocation (46%), incorrect IOL power (23%), patient dissatisfaction (Read more...)
The Diurnal and Nocturnal Effect of Travoprost With SofZia on Intraocular Pressure and Ocular Perfusion Pressure – Corrected Proof
Purpose: To determine the 24-hour effects of travoprost with sofZia on intraocular pressure (IOP) and ocular perfusion pressure as well as the endurance of IOP lowering after last dosing.Design: Prospective, open-label study.Methods: Forty subjects with open-angle glaucoma or ocular hypertension were admitted to our sleep laboratory for three 24-hour sessions monitoring IOP, blood pressure (BP), and heart rate. The first baseline session occurred after medication washout or immediately after enrollment for treatment-naïve patients. A second 24-hour monitoring session was performed after 4 weeks of once-nightly treatment of travoprost with sofZia. The medication was then discontinued and a third 24-hour session was completed 60-84 hours after the (Read more...)
The Effect of Phacoemulsification on Intraocular Pressure in Medically Controlled Open-Angle Glaucoma Patients – Corrected Proof
Purpose: To evaluate intraocular pressure (IOP) after phacoemulsification in patients with medically controlled open-angle glaucoma (OAG), and examine the association of biometric variables to IOP changes.Design: Retrospective case series.Methods: Open-angle glaucoma patients without prior incisional glaucoma surgery undergoing phacoemulsification by a single surgeon between January 1997 and October 2011 were evaluated. Patient charts were reviewed to obtain demographic information, preoperative glaucoma medications, severity and treatment measures, and preoperative and postoperative IOP.Results: A total of 157 eyes (157 patients) were included in the study. The average preoperative IOP of 16.3 ± 3.6 mm Hg decreased to 14.5 ± 3.4 mm Hg at 1 (Read more...)
Corneal Topographic and Tomographic Analysis of Fellow Eyes in Unilateral Keratoconus Patients Using Pentacam – Corrected Proof
Purpose: To evaluate topographic and tomographic changes in fellow eyes in unilateral keratoconus (KCN) patients by comparing them with normal eyes.Design: Retrospective comparative case series.Methods: Fourteen eyes of 14 patients with unilateral KCN and 34 eyes of 34 refractive surgery candidates were divided into 3 diagnostic groups using a Pentacam rotating Scheimpflug camera: advanced KCN eyes of unilateral KCN (KCN group, 14 eyes), normal fellow eyes of unilateral KCN (fellow eye group, 14 eyes), and refractive surgery candidates (normal group, 34 eyes). Topographic and tomographic parameters, which were obtained from Pentacam using sagittal curvature, elevation, and corneal thickness maps, were (Read more...)
Visual Impairment Corrected Via Cataract Surgery and 5-Year Survival in a Prospective Cohort – Corrected Proof
Purpose: To compare mortality risk between cataract surgical patients with corrected and persistent visual impairment.Design: Cohort study.Methods: A total of 1864 consecutive patients, aged ≥64 years, undergoing phacoemulsification surgery at Westmead Hospital were followed annually for 5 years postoperatively. Visual impairment status in the surgical eye was categorized as none (presenting visual acuity [VA], ≥20/40), mild (VA <20/40-20/60), or moderate-severe (VA <20/60). All-cause mortality was obtained from the Australian National Death Index.Results: Of 901 patients with moderate-severe visual impairment before surgery, 60.4% (n = 544), 15.5% (n = 140), and 24.1% (n = 217) had no, mild, or moderate-severe visual impairment in the (Read more...)
Ocular and Optical Coherence Tomography–Based Corneal Aberrometry in Keratoconic Eyes Treated by Intracorneal Ring Segments – Corrected Proof
Purpose: To analyze corneal and total aberrations using custom-developed anterior segment spectral optical coherence tomography (OCT) and laser ray tracing in keratoconic eyes implanted with intracorneal ring segments (ICRS).Design: Evaluation of techn…
Parallelism as a Novel Marker for Structural Integrity of Retinal Layers in Optical Coherence Tomographic Images in Eyes With Epiretinal Membrane – Corrected Proof
Purpose: To propose a new parameter, “Parallelism,” to evaluate retinal layer integrity on spectral-domain optical coherence tomography (SDOCT), and to investigate the association between parallelism and visual function in eyes with idiopathic epiretinal membrane (ERM).Design: Retrospective, observational evaluation of a diagnostic test.Methods: We evaluated a consecutive series of 57 eyes of 57 patients with ERM and 30 healthy eyes of 30 volunteers for whom M-CHARTS testing and SDOCT were performed on the same day. OCT images were skeletonized, and the orientation of segmented lines in the image was termed “Parallelism” and was expressed as a value ranging from 0-1 and (Read more...)
Extended Depth of Focus With Induced Spherical Aberration in Light-Adjustable Intraocular Lenses – Corrected Proof
Purpose: To evaluate the quality of vision and depth of focus induced by controlled amounts of negative spherical aberration in patients implanted bilaterally with light-adjustable intraocular lenses.Design: Prospective, nonrandomized clinical trial.Methods: Seventeen patients were implanted and treated with appropriate spatial irradiance light profiles. One eye was set for emmetropia, and the fellow eye received an additional aspheric light treatment to induce controlled amounts of negative spherical aberration. We used a Hartmann-Shack sensor to measure the eye’s refraction and aberrations for a 4-mm pupil diameter. Decimal visual acuity (VA) was measured using a micro-display placed at 10 m, 60 cm, 40 cm, and (Read more...)
Three-Year Incidence and Factors Associated With Posterior Capsule Opacification After Cataract Surgery: The Australian Prospective Cataract Surgery and Age-related Macular Degeneration Study – Corrected Proof
Purpose: To assess 3-year incidence and associated factors of posterior capsule opacification (PCO) after phacoemulsification surgery.Design: Cohort study.Methods: A total of 1934 consecutive patients aged ≥64 years undergoing phacoemulsification sur…
Eyelid Sebaceous Carcinoma: Clinicopathologic and Multiparametric Immunohistochemical Analysis That Includes Adipophilin – Corrected Proof
Purpose: To evaluate the fine cytopathologic features and immunohistochemistry of eyelid sebaceous carcinoma.Design: Retrospective clinicopathologic study.Methods: Clinical records and microscopic glass slides of 12 patients diagnosed with sebaceous ca…
Visual and Refractive Outcomes of Femtosecond Lenticule Extraction and Small-Incision Lenticule Extraction for Myopia – Corrected Proof
Purpose: To compare the visual and refractive outcomes of femtosecond lenticule extraction (FLEx) and small-incision lenticule extraction (SMILE) in eyes with myopia.Design: Prospective, randomized, masked clinical trial with intraindividual comparison…
Randomized Controlled Trial of Intravitreal Ranibizumab Versus Standard Grid Laser for Macular Edema Following Branch Retinal Vein Occlusion – Corrected Proof
Purpose: To assess the efficacy of intravitreal 0.5 mg ranibizumab for the treatment of center-involving macular edema secondary to branch retinal vein occlusion (BRVO) over 1 year compared with standard-of-care grid laser.Design: A prospective random…
Intraocular Lens Power Calculation by Ray-Tracing after Myopic Excimer Laser Surgery – Corrected Proof
Purpose: To investigate the refractive outcomes of intraocular lens (IOL) power calculation by ray-tracing after myopic excimer laser surgery.Design: Prospective, interventional case series.Methods: setting: Multicenter study. participants: Twenty-one …
Epidemiology and Disease Burden of Pathologic Myopia and Myopic Choroidal Neovascularization: An Evidence-Based Systematic Review – Corrected Proof
Purpose: To summarize the epidemiology of pathologic myopia and myopic choroidal neovascularization (CNV) and their impact on vision.Design: Systematic literature review of all English-language studies evaluating the epidemiology and visual burden of p…
KRT12 Mutations and In Vivo Confocal Microscopy in Two Japanese Families With Meesmann Corneal Dystrophy – Corrected Proof
Purpose: To identify genetic mutations and study the corneal epithelium in Japanese patients with Meesmann corneal dystrophy.Design: Laboratory investigation and prospective observational case series.Methods: Slit-lamp biomicroscopy with fluorescein vi…
Metamorphopsia and Optical Coherence Tomography Findings After Rhegmatogenous Retinal Detachment Surgery – Corrected Proof
Purpose: To investigate the relationship between metamorphopsia and macular morphologic changes after successful repair of rhegmatogenous retinal detachment (RD).Design: Prospective, interventional, consecutive study.Methods: The study included 129 eyes of 129 patients who had undergone successful retinal reattachment surgery. The severity of metamorphopsia was recorded using M-CHARTS and foveal microstructure was assessed with spectral-domain optical coherence tomography (OCT) at 6-12 months postoperatively.Results: The mean metamorphopsia score was 0.30 ± 0.46, and 50 of 129 patients (39%) had metamorphopsia. Metamorphopsia was more severe in eyes with macula-off rhegmatogenous RD than those with macula-on (P < .001). Eighteen of 50 eyes with metamorphopsia exhibited abnormal structures (Read more...)
Evaluation of Levator Function for Efficacy of Minimally Invasive and Standard Techniques for Involutional Ptosis – Corrected Proof
Purpose: To evaluate clinical and anatomic outcomes of surgery for involutional ptosis using standard-length or small incisions in relation to preoperative levator function.Design: Retrospective study.Methods: Sixty-three patients diagnosed with involutional ptosis who underwent surgical correction using a small or standard-length incision between November 2010 and December 2011 were reviewed; a single surgeon performed surgery using a small incision (8 to 10 mm) in 22 patients and a standard-length incision (20 to 22 mm) in 34 patients. All patients underwent standard preoperative ptosis evaluation with margin-to-reflex distance 1 and 2 measurements and levator function assessment. Patients were divided into 2 groups according to (Read more...)