The study presented by Man et al contributes to our understanding of the pathophysiology of diabetic retinopathy (DR) by demonstrating, in a large clinical study, that eyes with longer axial length are less likely to have DR or diabetic macular edema. …
Category: Peer-reviewed
Erlotinib-related Corneal Melting
We read with interest the article entitled, “Ocular Adverse Events of Systemic Inhibitors of the Epidermal Growth Factor Receptor: Report of 5 Cases” by Saint-Jean et al. The severity of ocular toxicities of epidermal growth factor (EGF) receptor i…
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Arjmand et al in a recent letter to the editor emphasized the importance of various health and non–health-related factors that affect the caregiver–patient relationship. We thank Arjmand et al for their commentary; their contribution is welcome.
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We read with great interest the letter by Quigley and Brown regarding the possible mechanisms behind the reduced intravascular pressure in eyes with an elongated ocular axis. Their explanation offers an even more in-depth insight into how this reductio…
Gene Expression Profiling versus TNM Classification
We respectfully wish to draw attention to the way in which the Tumor, Node, Metastasis (TNM) classification of the American Joint Committee on Cancer (AJCC) was applied by Onken et al in their validation of a multigene prognostic assay in patients with…
Cognitive Impairment in AMD
Woo et al’s study examining the close association of senile neurodegenerative diseases age-related macular degeneration (AMD) and Alzheimer disease concludes that individuals with AMD are at greater risk for cognitive impairment. This assertion merits …
Tuberculosis of Eyelid Presenting as a Chalazion
Inflammatory and neoplastic lesions of the eyelid may present clinically as a primary or recurrent chalazion. We present a case of isolated unilateral tuberculosis of the eyelid masquerading as a partially prolapsed chalazion, missed initially because …
Caregiver Burden in Ocular Disease
Braich et al report a correlation between the degree of visual impairment and caregiver depression, in the context of a large scale study and use of quantitative methods. They describe intensity of care, number of hours spent providing care, low househ…
Long-term Risk of Glaucoma After Congenital Cataract Surgery – Corrected Proof
Purpose: To report the long-term risk of glaucoma development in children following congenital cataract surgery.Design: Retrospective interventional consecutive case series.Methods: We retrospectively reviewed the records of 62 eyes of 37 children who underwent congenital cataract surgery when <7 months of age by the same surgeon using a limbal approach. The Kaplan-Meier method was used to calculate the probability of an eye’s developing glaucoma and/or becoming a glaucoma suspect over time.Results: The median age of surgery was 2.0 months and the median follow-up after cataract surgery was 7.9 years (range, 3.2-23.5 years). Nine eyes (14.5%) developed glaucoma a median of 4.3 months after cataract surgery and an additional 16 eyes (25.8%) were diagnosed as glaucoma suspects a median of 8.0 years after cataract surgery. The probability of an eye’s developing glaucoma was estimated to be 19.5% (95% CI: 10.0%-36.1%) by 10 years after congenital cataract surgery. When the probability of glaucoma and glaucoma suspect were combined, the risk increased to 63.0% (95% CI: 43.6%-82.3%).Conclusions: Long-term monitoring of eyes after congenital cataract surgery is important because we estimate that nearly two thirds of these eyes will develop glaucoma or become glaucoma suspects by 10 years after cataract surgery.
Serous Macular Detachment in Waldenström Macroglobulinemia: A Report of 4 Cases
We read with great interest the article by Baker and associates. These authors examined the effects of Waldenström disease on 4 patients with serous macular detachment. Immunoglobulin M was identified in the subretinal space and all retinal layers in …
AJO History of Ophthalmology Series: Wilhelm Kühne and Optograms
Soon after the discovery of “visual purple” or rhodopsin by physiologist Franz Boll of the University of Rome in 1876, Wilhelm “Willy” Friedrick Kühne (1837-1900), a physiologist and Helmhotz’s successor in Heidelberg, intensely studied its pr…
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We appreciate the comment of Fingerhut and associates regarding our study of photodynamic therapy (PDT) with or without intravitreal bevacizumab for polypoidal choroidal vasculopathy (PCV). They raise the question of the timing of the intravitreal beva…
Pediatric Neuro-Ophthalmology, Second Edition
Media Type: Textbook Synopsis: The explosive growth in our understanding of the nervous system over the past 30 years has been accompanied by parallel growth of knowledge in related medical fields such as pediatric neuro-ophthalmology. The second edi…
Macular Surgery, Second Edition
Media Type: Textbook with On-line text and image bank (requires activation) Synopsis: The second edition of Macular Surgery is a well-written, comprehensive, and current review of macular diseases as well as their clinical and surgical management. Th…
Photodynamic Therapy With or Without Intravitreal Bevacizumab for Polypoidal Choroidal Vasculopathy: Two Years of Follow-up
We read with great interest the article by Lee and associates comparing the efficacy of photodynamic therapy (PDT) with and without intravitreal bevacizumab (IVB) injections for the treatment of polypoidal choroidal vasculopathy (PCV). We were surprise…
Premium Cataract Surgery: A Step-By-Step Guide
Media Type: Textbook (Hardcover) Synopsis: Premium Cataract Surgery, as the title may indicate, is providing a service for patients who are in need for cataract surgery something more than an average cataract patient may receive. It can be in the for…
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We thank Caimi and associates for their interest in our article regarding serous macular detachment in Waldenström macroglobulinemia. They describe 1 patient in whom cystoid macular edema and serous macular detachment was present without outer retinal…
Obituary: Alberto Urrets-Zavalía Jr, MD, PhD (1920-2010)
Dr Alberto Urrets-Zavalía Jr, who passed away on July 31, 2010, at the age of 89, was one of the most influential Argentine ophthalmologists of the 20th century. Born in Córdoba (Argentina) on September 30, 1920, he was the son of a nationally ren…
Techniques in Ophthalmic Plastic Surgery: A Personal Tutorial
Media Type: Textbook (Hardcover) and DVD Synopsis: Techniques in Ophthalmic Plastic Surgery: A Personal Tutorial, is based on Dr Nerad’s previously well-acclaimed Requisites in Oculoplastic Surgery that appeared in 2001. The author has kept the same …