Category: Peer-reviewed
Reply
We appreciate the interest and comments on our recently published manuscript, “Clinical and Microbiological Profile of Post-Penetrating Keratoplasty Infectious Keratitis in Failed and Clear Grafts.” In this retrospective analysis, we found that pat…
Restricting Topical Ocular Chloramphenicol Eye Drop Use in the United States. Did We Overreact?
Topical ocular chloramphenicol eye drops are relatively inexpensive and have broad-spectrum coverage of most gram-positive, gram-negative, and anaerobic bacteria. Worldwide, it is estimated that more than 50% of the world use topical chloramphenicol as…
Ocular Flora and Their Antibiotic Resistance Patterns in the Midwest: A Prospective Study of Patients Undergoing Cataract Surgery
We read with interest the article by Hsu and associates on ocular flora and antibiotic resistance in patients undergoing cataract surgery. As the authors indicated, the most common prophylactic practice in many countries outside Europe is perioperative…
Contents
The Phillips Thygeson Experiment in Trachoma
In the 1930s Phillips Thygeson and his associates were performing experiments to prove that the elementary bodies from the Halberstaedter-Prowazek inclusions were the infectious agent of trachoma. Using epithelium scraped from the eyes of infected chil…
Long-term Risk of Glaucoma After Congenital Cataract Surgery
We read with great interest the article published by Lambert and associates. They have highlighted a very important complication after pediatric cataract surgery. There are certain issues that need to be addressed. The authors enrolled 62 eyes of 37 pa…
Reply
We appreciate the interest of Carifi and associates in our recent article. They have raised some excellent points regarding the limitations of our study, some of which we acknowledged in the article. Since our study was retrospective and included patie…
Wills Eye Institute 5-Minute Ophthalmology Consult
Media Type: Textbook Target Audience: General ophthalmologists, ophthalmology residents and fellows
Ultrasound Biomicroscopy of the Ciliary Body in Ocular/Oculodermal Melanocytosis
We read with great interest and attention the recent article from Velazquez-Martin and associates regarding the evaluation of ciliary body thickness in eyes of patients with unilateral ocular/oculodermal melanocytosis. They concluded that ciliary body …
Reply
We appreciate the interest shown in our article. We agree that the Wilcoxon signed-rank test would be more appropriate. We have run the data using this test and have found that the results are statistically significantly consistent with the results usi…
Headache or Eye Pain as the Presenting Feature of Uveal Melanoma
Uveal melanoma classically presents as a painless intraocular mass. Related features such as retinal detachment, vitreous hemorrhage, or extraocular extension, typically do not generate pain. Pain is rare, found in <1% of cases, and can be caused by severely elevated intraocular pressure from neovascular or angle-closure glaucoma, or it can result from spontaneous tumor necrosis. Often there is delay in diagnosis as the headache or ocular pain is attributed to sinusitis, dental infection, muscle or emotional stress, or migraine etiology.
Intracameral Cyclosporine Drug Delivery System in High-risk Keratoplasty
We read with great interest the innovative work of Shi et al on cyclosporine intraocular drug delivery system for high-risk keratoplasty. It is not true that endothelial graft rejection often occurs within 2 weeks after transplantation, as authors sta…
Author reply
We thank Prajna et al for their comments on our article titled, “Comparative evaluation of topical versus intrastromal voriconazole as an adjunct to natamycin in recalcitrant fungal keratitis.” At the time of our publication, 1 study had been publ…
Prevalence and Risk Factors for Developing Ophthalmic Manifestations in Pediatric Human Immunodeficiency Virus Infection
There are 3.4 million HIV-infected children worldwide and reports suggest that every hour about 30 children die as a result of AIDS. Although pediatric HIV infection in developing countries is on the rise, developed countries have noted a decline. Ocul…
Two Year SAVE Outcomes: 2.0 mg Ranibizumab for Recalcitrant Neovascular AMD
The Super-dose Anti-VEGF (SAVE) trial assessed the efficacy of 2.0 mg ranibizumab (0.05 ml), a 4-fold higher dose than the 0.5 mg dose approved by the US Food and Drug Administration, for the management of recalcitrant neovascular age-related macular d…
Other Considerations in Pterygium Surgery
The Ophthalmic Technology Assessment (OTA) is a valuable and timely assessment of the techniques that might be used for pterygium surgery and focusses attention on 2 aspects of pterygium surgery, namely recurrence rates and complications of the various…
Change in Prostaglandin Expression Levels and Synthesizing Activities
We read with great interest the recently published study by Shim et al, which the authors described as a cross-sectional, case-control, clinical trial. As a single study, such a design is not possible because cross-sectional, case-control, and clinica…
Editorial Board
Voriconazole for Fungal Keratitis
In their recently published trial, Sharma et al found topical voriconazole to be more effective than intrastromal voriconazole when added to topical natamycin in patients with recalcitrant fungal keratitis. This trial shares a similar protocol with se…